Tweet
J Infect Dis
. 2026 May 31:jiag283.
doi: 10.1093/infdis/jiag283. Online ahead of print.
Risk of hospitalization related to influenza A(H3N2) virus subclade K, Thailand, June-December 2025
Kriengkrai Prasert 1 , Prabda Praphasiri 2 , Darunee Ditsungnoen 3 , Suriya Naosri 1 , Siripaporn Phuygun 4 , Sutthichai Nakphook 1 , Seesai Yeesoonsang 5 , Jatuporn Saiyarin 6 , Nuttida Thongpramul 4 , Apinya Panjangampatthana 5 , Melissa A Rolfes 7 , William W Davis 3 7 , Martha P Montgomery 3 7 , Pilailuk Akkapaiboon Okada 4 , Wichan Bhunyakitikorn 5
Affiliations
Antigenically drifted influenza A(H3N2) subclade K viruses have contributed substantially to influenza burden since 2025, but their clinical severity is less well described. Using sentinel surveillance data from Thailand, we found no significant difference in the adjusted odds of hospitalization among those infected with subclade K versus other influenza viruses (adjusted odds ratio 1.06, 95% confidence interval 0.67, 1.68). This approach to estimating hospitalization risk for an emerging influenza virus subclade using sentinel surveillance data could serve as a model for conducting future rapid assessments.
Keywords: Case-control studies; H3N2 subtype; Human influenza; Influenza A virus; Sentinel surveillance.
. 2026 May 31:jiag283.
doi: 10.1093/infdis/jiag283. Online ahead of print.
Risk of hospitalization related to influenza A(H3N2) virus subclade K, Thailand, June-December 2025
Kriengkrai Prasert 1 , Prabda Praphasiri 2 , Darunee Ditsungnoen 3 , Suriya Naosri 1 , Siripaporn Phuygun 4 , Sutthichai Nakphook 1 , Seesai Yeesoonsang 5 , Jatuporn Saiyarin 6 , Nuttida Thongpramul 4 , Apinya Panjangampatthana 5 , Melissa A Rolfes 7 , William W Davis 3 7 , Martha P Montgomery 3 7 , Pilailuk Akkapaiboon Okada 4 , Wichan Bhunyakitikorn 5
Affiliations
- PMID: 42217493
- DOI: 10.1093/infdis/jiag283
Antigenically drifted influenza A(H3N2) subclade K viruses have contributed substantially to influenza burden since 2025, but their clinical severity is less well described. Using sentinel surveillance data from Thailand, we found no significant difference in the adjusted odds of hospitalization among those infected with subclade K versus other influenza viruses (adjusted odds ratio 1.06, 95% confidence interval 0.67, 1.68). This approach to estimating hospitalization risk for an emerging influenza virus subclade using sentinel surveillance data could serve as a model for conducting future rapid assessments.
Keywords: Case-control studies; H3N2 subtype; Human influenza; Influenza A virus; Sentinel surveillance.