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J Cardiol Cases
. 2023 Oct 13;29(1):15-18.
doi: 10.1016/j.jccase.2023.09.006. eCollection 2024 Jan. Recurrent left ventricular thrombus due to essential thrombocythemia complicated by COVID-19
Kenta Matsui 1 , Tadashi Kitamura 1 , Shinzo Torii 1 , Toshiaki Mishima 1 , Fumiaki Shikata 1 , Masaomi Fukuzumi 1 , Shunichiro Fujioka 1 , Haruna Araki 1 , Rihito Horikoshi 1 , Yoshimi Tamura 1 , Hisaya Mori 1 , Kagami Miyaji 1
Affiliations
Essential thrombocythemia is a risk factor for thrombosis and hemorrhage. During the perioperative period of cardiac surgery, the risk of thrombosis and hemorrhage increases. Coronavirus disease 2019 (COVID-19) is also associated with thrombosis. We present the case of a 69-year-old man with essential thrombocythemia complicated by COVID-19 who developed a left ventricular thrombus. We performed thrombectomy, but the patient developed recurrent left ventricular thrombus 8 days after surgery. Emergency redo thrombectomy was performed followed by aggressive blood-thinning therapy. The postoperative course was complicated by cardiac tamponade requiring surgical drainage 8 days after the second surgery. The patient was discharged home 25 days after the second operation without any complications.
Learning objective: Left ventricular thrombus is a rare but fatal complication associated with essential thrombocythemia. COVID-19 has also been reported to cause coagulopathy. This case suggested that after surgery for left ventricular thrombus complicated by multiple risk factors including essential thrombocythemia and COVID-19, aggressive blood-thinning therapy with combination of anticoagulation, antiplatelet, and metabolic antagonist may help prevent recurrent thrombosis.
Keywords: COVID-19; Essential thrombocythemia; Left ventricular thrombus.
. 2023 Oct 13;29(1):15-18.
doi: 10.1016/j.jccase.2023.09.006. eCollection 2024 Jan. Recurrent left ventricular thrombus due to essential thrombocythemia complicated by COVID-19
Kenta Matsui 1 , Tadashi Kitamura 1 , Shinzo Torii 1 , Toshiaki Mishima 1 , Fumiaki Shikata 1 , Masaomi Fukuzumi 1 , Shunichiro Fujioka 1 , Haruna Araki 1 , Rihito Horikoshi 1 , Yoshimi Tamura 1 , Hisaya Mori 1 , Kagami Miyaji 1
Affiliations
- PMID: 38188321
- PMCID: PMC10770075
- DOI: 10.1016/j.jccase.2023.09.006
Essential thrombocythemia is a risk factor for thrombosis and hemorrhage. During the perioperative period of cardiac surgery, the risk of thrombosis and hemorrhage increases. Coronavirus disease 2019 (COVID-19) is also associated with thrombosis. We present the case of a 69-year-old man with essential thrombocythemia complicated by COVID-19 who developed a left ventricular thrombus. We performed thrombectomy, but the patient developed recurrent left ventricular thrombus 8 days after surgery. Emergency redo thrombectomy was performed followed by aggressive blood-thinning therapy. The postoperative course was complicated by cardiac tamponade requiring surgical drainage 8 days after the second surgery. The patient was discharged home 25 days after the second operation without any complications.
Learning objective: Left ventricular thrombus is a rare but fatal complication associated with essential thrombocythemia. COVID-19 has also been reported to cause coagulopathy. This case suggested that after surgery for left ventricular thrombus complicated by multiple risk factors including essential thrombocythemia and COVID-19, aggressive blood-thinning therapy with combination of anticoagulation, antiplatelet, and metabolic antagonist may help prevent recurrent thrombosis.
Keywords: COVID-19; Essential thrombocythemia; Left ventricular thrombus.
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