Heliyon . Case Report of a Young Adult with Fatal COVID-19 and Abundant SARS-CoV-2 Nucleocapsid Protein and Lipofuscin Accumulation in Tissues

[tetano]

Heliyon


. 2023 Dec 10;10(1):e23485.
doi: 10.1016/j.heliyon.2023.e23485. eCollection 2024 Jan 15. Case Report of a Young Adult with Fatal COVID-19 and Abundant SARS-CoV-2 Nucleocapsid Protein and Lipofuscin Accumulation in Tissues

Rosalia Lira ¹ , César Luna-Rivero ² , Francina Valezka Morales-Bolaños ³ , José Luis Sandoval-Gutiérrez ⁴ , Elsa Romelia Moreno-Verduzco ⁵ , Angélica Maldonado-Rodriguez ⁶ , Jesús Miguel Torres-Flores ⁷ , Martha Yocupicio-Monroy ⁸ , Edgar E Sevilla-Reyes ^{9 10}



Affiliations

• PMID: 38173536
• PMCID: PMC10761569
• DOI: 10.1016/j.heliyon.2023.e23485

Abstract

This is a case report of a young adult who died of COVID-19 twelve days after admission, with coronavirus nucleocapsid protein and lipofuscin found in the heart and kidney tissues, providing further evidence of the role of SARS-CoV-2 in cellular senescence.

Keywords: COVID-19; Case report; Muscle; Nucleocapsid protein; lipofuscin.

[sharon sanders]

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