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Clin Infect Dis . Lower Risk of Multisystem Inflammatory Syndrome in Children (MIS-C) with the Delta and Omicron variants of SARS-CoV-2

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    Clin Infect Dis . Lower Risk of Multisystem Inflammatory Syndrome in Children (MIS-C) with the Delta and Omicron variants of SARS-CoV-2


    Clin Infect Dis


    . 2022 Jul 5;ciac553.
    doi: 10.1093/cid/ciac553. Online ahead of print.
    Lower Risk of Multisystem Inflammatory Syndrome in Children (MIS-C) with the Delta and Omicron variants of SARS-CoV-2


    Jonathan M Cohen 1 2 , Michael J Carter 3 4 , C Ronny Cheung 5 6 , Shamez Ladhani 7 8 , Evelina PIMS-TS Study Group



    Affiliations

    Abstract

    Little is known about the MIS-C risk with different SARS-CoV-2 variants. In Southeast England, MIS-C rates per confirmed SARS-CoV-2 infections in 0-16 years-olds were 56% lower (rate ratio, 0.34; 95%CI, 0.23-0.50) during pre-vaccine Delta, 66% lower (0.44; 0.28-0.69) during post-vaccine Delta and 95% lower (0.05; 0.02-0.10) during the Omicron period.

    Keywords: COVID-19; MIS-C; PIMS-TS; SARS-CoV-2; coronavirus.

    Tags: None
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