Nat Cancer
. 2022 Apr 4.
doi: 10.1038/s43018-022-00363-4. Online ahead of print.
Outcomes of COVID-19 and risk factors in patients with cancer
Manju Sengar # 1 , Girish Chinnaswamy # 1 , Priya Ranganathan 1 , Apurva Ashok 1 , Shilpushp Bhosale 1 , Sanjay Biswas 1 , Pankaj Chaturvedi 1 , Chetan Dhamne 1 , Jigeeshu Divatia 1 , Karishma D'Sa 1 , Hasmukh Jain 1 , Sarbani Laskar 1 , Nirmalya Roy Moulik 1 , Naveen Mummudi 1 , Sindhu Nair 1 , Lingaraj Nayak 1 , Prakash Nayak 1 , Shraddha Patkar 1 , Preeti Pawaskar 1 , Anant Ramaswamy 1 , Omshree Shetty 1 , Arjun Singh 1 , Epari Sridhar 1 , Jayashree Thorat 1 , Rajendra Badwe 1 , C S Pramesh 2 , TMH COVID-19 action group
Collaborators, Affiliations
- PMID: 35379984
- DOI: 10.1038/s43018-022-00363-4
Abstract
Patients with cancer are at higher risk for adverse coronavirus disease 2019 (COVID-19) outcomes. Here, we studied 1,253 patients with cancer, who were diagnosed with severe acute respiratory syndrome coronavirus 2 at a tertiary referral cancer center in India. Most patients had mild disease; in our settings, recent cancer therapies did not impact COVID-19 outcomes. Advancing age, smoking history, concurrent comorbidities and palliative intent of treatment were independently associated with severe COVID-19 or death. Thus, our study provides useful insights into cancer management during the COVID-19 pandemic.