Rev Soc Bras Med Trop . Systemic inflammatory syndrome in children during COVID-19 pandemic in Ceará state, northeastern Brazil: an observational study

[tetano]

Rev Soc Bras Med Trop


. 2021 Nov 12;54:e0383.
doi: 10.1590/0037-8682-0383-2021. eCollection 2021.
Systemic inflammatory syndrome in children during COVID-19 pandemic in Ceará state, northeastern Brazil: an observational study


Luís Arthur Brasil Gadelha Farias ¹ , Magda Moura de Almeida ^{2 3} , Pâmela Maria Costa Linhares ² , Bruno Cavalcante Fales de Brito Alves ⁴ , Roberto Jorge Colares Duarte Filho ³ , Roberio Dias Leite ^{1 3} , Marco Aurelio Palazzi Safadi ⁵ , Luciano Pamplona de Góes Cavalcanti ^{3 4}



Affiliations

• PMID: 34787262
• DOI: 10.1590/0037-8682-0383-2021

Abstract

In this study, we report the occurrence of multisystemic inflammatory syndrome among 64 children (2 deaths) with recent severe acute respiratory syndrome-related coronavirus 2 (SARS-COV-2) infections in the northeast region of Brazil. The major clinical symptoms and signs reported were exanthema (60.9%), abdominal pain (56.3%), nausea and vomiting (46.9%), diarrhea (37.5%), and dyspnea (37.5%). Laboratory findings revealed that the levels of C-reactive protein (75.0%), hemoglobin (51.6%), D-dimer (48.4%), lymphocytes (43.8%), LDH (45.3%), AST (42.2%), ALT (51.6%), and ferritin (48.4%) were above the reference values for a given age and gender. The clinical findings were similar to those observed in Kawasaki disease, although it represents a separate entity, emphasizing the need for proactive surveillance and early treatment.