Tweet
Pediatr Infect Dis J
. 2021 Sep 28.
doi: 10.1097/INF.0000000000003358. Online ahead of print.
Acute Cerebellitis in MIS-C: A Case Report
Nihal Akçay 1 , Mustafa Oğur, Mehmet Emin Menentoğlu, Ayşe İrem Sofuoğlu, Kübra Boydağ Güvenç, Figen Bakirtaş Palabiyik, Esra Şevketoğlu
Affiliations
- PMID: 34596624
- DOI: 10.1097/INF.0000000000003358
Abstract
Background: Coronavirus disease-2019 (COVID-19) is characterized predominantly by respiratory symptoms and has affected a small subset of children. Multisystem inflammatory syndrome in children (MIS-C) has been reported in children following COVID-19. There is increasing report that COVID-19 may also lead to neurologic manifestations. Cerebellar lesions may be observed in viral infections.
Case report: We report a child with MIS-C related to severe acute respiratory syndrome coronavirus 2, who developed cerebellar lesion during the disease course. Encephalopathy was the first central nervous system symptom. His consciousness improved but he developed clinical signs of cerebellar dysfunction including ataxia, dysarthria and nystagmus. Brain magnetic resonance imaging (MRI) revealed symmetrical pathological signal changes in both cerebellar hemispheres.
Conclusion: We demonstrated the first child with MIS-C to develop cerebellar lesion on brain MRI, suggestive of cerebellitis.