Open Forum Infect Dis . Clinical Symptoms Among Ambulatory Patients Tested for SARS-CoV-2

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Open Forum Infect Dis


. 2020 Nov 26;8(1):ofaa576.
doi: 10.1093/ofid/ofaa576. eCollection 2021 Jan.
Clinical Symptoms Among Ambulatory Patients Tested for SARS-CoV-2


Jessie R Chung ¹ , Sara S Kim ¹ , Michael L Jackson ² , Lisa A Jackson ² , Edward A Belongia ³ , Jennifer P King ³ , Richard K Zimmerman ⁴ , Mary Patricia Nowalk ⁴ , Emily T Martin ⁵ , Arnold S Monto ⁵ , Manjusha Gaglani ⁶ , Michael E Smith ⁶ , Manish Patel ¹ , Brendan Flannery ¹



Affiliations

• PMID: 33537361
• PMCID: PMC7717425
• DOI: 10.1093/ofid/ofaa576

Abstract

We compared symptoms and characteristics of 4961 ambulatory patients with and without laboratory-confirmed severe acute respiratory syndrome coronavirus 2 infection. Findings indicate that clinical symptoms alone would be insufficient to distinguish between coronavirus disease 2019 and other respiratory infections (eg, influenza) and/or to evaluate the effects of preventive interventions (eg, vaccinations).

Keywords: COVID-19; case definitions; influenza; observational research studies; vaccine effectiveness.