BMC Pregnancy Childbirth . SARS-COV-2 infection during pregnancy, a risk factor for eclampsia or neurological manifestations of COVID-19? Case report

[tetano]

BMC Pregnancy Childbirth


. 2020 Oct 6;20(1):587.
doi: 10.1186/s12884-020-03275-2.
SARS-COV-2 infection during pregnancy, a risk factor for eclampsia or neurological manifestations of COVID-19? Case report


Alejandro Garcia Rodriguez ¹ , Sergio Marcos Contreras ² , Santiago Manuel Fernandez Manovel ¹ , Jose Miguel Marcos Vidal ¹ , Fernando Diez Buron ¹ , Camino Fernandez Fernandez ³ , Maria Del Carmen Riveira Gonzalez ⁴



Affiliations

• PMID: 33023500
• DOI: 10.1186/s12884-020-03275-2

Abstract

Background: There are no published cases of tonic-clonic seizures and posterior bilateral blindness during pregnancy and Severe Acute Respiratory Syndrome (SARS) Coronavirus (COV) 2 (SARS-COV-2) infection. We do not just face new and unknown manifestations, but also how different patient groups are affected by SARS-COV-2 infection, such as pregnant women. Coronavirus Disease 2019 (COVID-19), preeclampsia, eclampsia and posterior reversible leukoencephalopathy share endothelium damage and similar pathophysiology.
Case presentation: A 35-year-old pregnant woman was admitted for tonic-clonic seizures and SARS-COV-2 infection. She had a normal pregnancy control and no other symptoms before tonic-clonic seizures development. After a Caesarean section (C-section) she developed high blood pressure, and we initiated antihypertensive treatment with labetalol, amlodipine and captopril. Few hours later she developed symptoms of cortical blindness that resolved in 72 h with normal brain computed tomography (CT) angiography.
Conclusion: The authors conclude that SARS COV-2 infection could promote brain endothelial damage and facilitate neurological complications during pregnancy.

Keywords: COVID-19; Case-report; Neurological manifestations; Preeclampsia; Pregnancy.