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Pediatr Infect Dis J . SERUM RESPONSES OF CHILDREN WITH KAWASAKI DISEASE AGAINST SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 PROTEINS

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  • Pediatr Infect Dis J . SERUM RESPONSES OF CHILDREN WITH KAWASAKI DISEASE AGAINST SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 PROTEINS


    Pediatr Infect Dis J


    . 2020 Aug 12.
    doi: 10.1097/INF.0000000000002863. Online ahead of print.
    SERUM RESPONSES OF CHILDREN WITH KAWASAKI DISEASE AGAINST SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 PROTEINS


    Arthur J Chang 1 , Michael Croix, Patrick Kenney, Sarah Baron, Mark D Hicar



    Affiliations

    Abstract

    With recent reports showing clinical and laboratory overlap of multisystem inflammatory syndrome in children and Kawasaki disease (KD), we addressed the hypothesis that cross coronavirus humoral immunity leads to a parallel postinfectious phenomenon explaining similar pathologic findings in KD and multisystem inflammatory syndrome in children. We demonstrated no cross-reactivity in children with KD but observed some nonspecific interactions postintravenous immunoglobulin infusion.


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