Pediatr Infect Dis J
. 2020 Aug 12.
doi: 10.1097/INF.0000000000002863. Online ahead of print.
SERUM RESPONSES OF CHILDREN WITH KAWASAKI DISEASE AGAINST SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 PROTEINS
Arthur J Chang 1 , Michael Croix, Patrick Kenney, Sarah Baron, Mark D Hicar
Affiliations
- PMID: 33021596
- DOI: 10.1097/INF.0000000000002863
Abstract
With recent reports showing clinical and laboratory overlap of multisystem inflammatory syndrome in children and Kawasaki disease (KD), we addressed the hypothesis that cross coronavirus humoral immunity leads to a parallel postinfectious phenomenon explaining similar pathologic findings in KD and multisystem inflammatory syndrome in children. We demonstrated no cross-reactivity in children with KD but observed some nonspecific interactions postintravenous immunoglobulin infusion.