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Ann Endocrinol (Paris) . THYROID DISORDERS AND SARS-CoV-2 INFECTION: from pathophysiological mechanism to patient management

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    Ann Endocrinol (Paris) . THYROID DISORDERS AND SARS-CoV-2 INFECTION: from pathophysiological mechanism to patient management


    Ann Endocrinol (Paris)


    . 2020 Sep 17;S0003-4266(20)31214-2.
    doi: 10.1016/j.ando.2020.09.001. Online ahead of print.
    THYROID DISORDERS AND SARS-CoV-2 INFECTION: from pathophysiological mechanism to patient management


    Philippe Caron 1



    Affiliations

    Abstract

    The World Health Organization (WHO) declared the COVID-19 epidemic to be a global pandemic in March 2020. COVID-19 is an infection caused by SARS-CoV-2, a coronavirus that utilizes the angiotensin-2 converting enzyme to penetrate thyroid and pituitary cells, and may result in a "cytokine storm". Based on the pathophysiological involvement of the pituitary-thyroid axis, the current review discusses the diagnosis of abnormal thyroid function test, and the management of patients presenting with thyrotoxicosis, thyroid-associated orbitopathy and hypothyroidism in the context of SARS-CoV-2 infection.

    Keywords: Covid-19; SARS-CoV-2; T3l; T4l; TSH; free T3; free T4; hypothyroidism; hypothyro?die; orbitopathie; orbitopathy; thyrotoxicose; thyrotoxicosis.

    Tags: None
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