Ann Vasc Surg . Acute lower limb ischemia as clinical presentation of COVID-19 infection

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Ann Vasc Surg


. 2020 Aug 10;S0890-5096(20)30642-7.
doi: 10.1016/j.avsg.2020.08.004. Online ahead of print.
Acute lower limb ischemia as clinical presentation of COVID-19 infection


Cristina Mietto ¹ , Valentina Salice ² , Matteo Ferraris ³ , Gianmarco Zuccon ³ , Federico Valdambrini ² , Giorgio Piazzalunga ³ , Anna Maria Socrate ³ , Danilo Radrizzani ²



Affiliations

• PMID: 32791191
• DOI: 10.1016/j.avsg.2020.08.004

Abstract

Novel 2019 coronavirus (COVID-19) infection usually causes a respiratory disease, that may vary in severity from mild symptoms to severe pneumonia with multiple organ failure. Coagulation abnormalities are frequent, and reports suggest that COVID-19 may predispose to venous and arterial thrombotic complications. We report a case of acute lower limb ischemia and resistance to heparin as the onset of COVID-19 disease, preceding the development of respiratory failure. This case highlights that the shift of coagulation profile towards hypercoagulability was associated with the acute ischemic event and influenced the therapy.

Keywords: COVID-19; SARS-CoV2; acute limb ischemia (ALI); arterial thrombosis; hypercoagulable states.