J Infect Dis . Clinical and epidemiological features of 46 children under 1 year old with coronavirus disease 2019 (COVID-19) in Wuhan, China: a descriptive study

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J Infect Dis


. 2020 Aug 6;jiaa472.
doi: 10.1093/infdis/jiaa472. Online ahead of print.
Clinical and epidemiological features of 46 children under 1 year old with coronavirus disease 2019 (COVID-19) in Wuhan, China: a descriptive study


Xinghua Liu ¹ , Rong Xie ² , Wei Li ¹ , Yan Guo ³ , Bo Zhang ² , Yue Zhang ² , Juanjuan Wang ⁴ , Cao Peng ⁵ , Xiao Lei ⁶ , Qunying Luo ⁶ , Qiong Zhang ⁶ , Jianqiao Tang ⁷ , Yunqiao Li ⁶ , Jianying Chen ¹



Affiliations

• PMID: 32761128
• DOI: 10.1093/infdis/jiaa472

Abstract

The number of COVID-19 cases has exceeded 10 million. However, little is known about the epidemiology and clinical characteristics of COVID-19 infants. We collected medical information of 46 confirmed patients (0-1 year old) and retrospectively analyzed epidemiological history, clinical symptoms, and laboratory test results. The median age is 5 (IQR, 2-7) months. Sixteen cases had fever and 27 cases had cough. Moderate disease was present in 40 cases and cardiac injury occurred in 38 cases, following by liver dysfunction in 20 cases and lymphocytosis in no cases.Of all infant patients, two received invasive mechanical ventilation and one died with MODS.

Keywords: SARS-CoV-2; children; clinical features; outcome.