J Thromb Thrombolysis Acute Pulmonary Embolism in COVID-19 Related Hypercoagulability

[tetano]

J Thromb Thrombolysis


. 2020 May 30;1-4.
doi: 10.1007/s11239-020-02160-1. Online ahead of print.
Acute Pulmonary Embolism in COVID-19 Related Hypercoagulability


Cerruti Lorenzo ¹ , Boscaro Francesca ¹ , Poletto Francesco ¹ , Campello Elena ¹ , Spiezia Luca ² , Simioni Paolo ¹



Affiliations

• PMID: 32474757
• PMCID: PMC7260472
• DOI: 10.1007/s11239-020-02160-1

Free PMC article

Abstract

Since December 2019, a novel Coronavirus (SARS-CoV-2) was confirmed as the etiologic agent of a worldwide outbreak of a pneumonia that can result in severe respiratory failure. This clinical entity seems to be associated with a marked hypercoagulable state that causes both arterial and venous thromboembolic complications. Therefore, an adequate anti-thrombotic prophylaxis is recommended in hospitalized COVID-19 patients. Although rapidly worsening respiratory symptoms in a patient with SARS-CoV-2 respiratory infection may correlate with worsening pneumonia itself, it may also mask a pulmonary embolism. We report the case of a 50-year-old man affected by SARS-CoV-2 pneumonia, who developed acute pulmonary embolism.

Keywords: COVID-19; Case report; Coagulation; Interstitial pneumonia; Pulmonary embolism; SARS-CoV-2.