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Eur J Med Res
. 2025 Jul 29;30(1):681.
doi: 10.1186/s40001-025-02733-x. Comparison of the clinical outcomes of COVID-19 in pregnant and non-pregnant patients of reproductive age
Nazila Karzad 1 , Simin Taghavi 2 , Ata Mahmoodpoor 3 , Seied Hadi Saghaleini 4 , Saeid Safiri 5 , Pouya Hosseinzadeh 6
Affiliations
Purpose: This study aims to compare the clinical course of COVID-19 in pregnant versus non-pregnant women aged 15-45 in Tabriz, focusing on disease severity, mortality, and pregnancy outcomes.
Methods: A total of 300 women were analyzed, with 150 pregnant and 150 non-pregnant participants. Data collected included demographic information, comorbidities, clinical outcomes, and pregnancy-related complications.
Results: The mean age of pregnant women was 32 years, while non-pregnant women averaged 38 years. Common comorbidities in the pregnant group included gestational diabetes and hypertension. Pregnant women predominantly experienced mild COVID-19 cases, whereas severe cases were more frequent in non-pregnant women; however, these differences were not statistically significant. Both groups had a mortality rate of 4.7%, with seven deaths reported in each cohort. Among pregnant women, 19% experienced preterm births, 6.7% had miscarriages, 3.5% had stillbirths, and 6.7% faced postpartum hemorrhages, with most preterm births being induced.
Conclusions: The findings suggest that pregnancy does not worsen the clinical course of COVID-19, as pregnant women generally exhibit milder symptoms and require fewer intensive care unit admissions compared to their non-pregnant counterparts.
Keywords: COVID-19; Morbidity; Mortality; Pregnancy; Women.
. 2025 Jul 29;30(1):681.
doi: 10.1186/s40001-025-02733-x. Comparison of the clinical outcomes of COVID-19 in pregnant and non-pregnant patients of reproductive age
Nazila Karzad 1 , Simin Taghavi 2 , Ata Mahmoodpoor 3 , Seied Hadi Saghaleini 4 , Saeid Safiri 5 , Pouya Hosseinzadeh 6
Affiliations
- PMID: 40731033
- PMCID: PMC12305978
- DOI: 10.1186/s40001-025-02733-x
Purpose: This study aims to compare the clinical course of COVID-19 in pregnant versus non-pregnant women aged 15-45 in Tabriz, focusing on disease severity, mortality, and pregnancy outcomes.
Methods: A total of 300 women were analyzed, with 150 pregnant and 150 non-pregnant participants. Data collected included demographic information, comorbidities, clinical outcomes, and pregnancy-related complications.
Results: The mean age of pregnant women was 32 years, while non-pregnant women averaged 38 years. Common comorbidities in the pregnant group included gestational diabetes and hypertension. Pregnant women predominantly experienced mild COVID-19 cases, whereas severe cases were more frequent in non-pregnant women; however, these differences were not statistically significant. Both groups had a mortality rate of 4.7%, with seven deaths reported in each cohort. Among pregnant women, 19% experienced preterm births, 6.7% had miscarriages, 3.5% had stillbirths, and 6.7% faced postpartum hemorrhages, with most preterm births being induced.
Conclusions: The findings suggest that pregnancy does not worsen the clinical course of COVID-19, as pregnant women generally exhibit milder symptoms and require fewer intensive care unit admissions compared to their non-pregnant counterparts.
Keywords: COVID-19; Morbidity; Mortality; Pregnancy; Women.