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Pediatr Infect Dis J. 2012 Feb 10. [Epub ahead of print]
Viral Coinfection in Children Less Than 5 Year-Old with Invasive Pneumococcal Disease.
Launes C, de-Sevilla MF, Selva L, Garcia-Garcia JJ, Pallares R, Mu?oz-Almagro C.
Source
*Infectious Diseases Unit, Department of Pediatrics, Hospital Sant Joan de Deu, Universitat de Barcelona, Spain ?Department of Molecular Microbiology, Hospital Sant Joan de Deu, Universitat de Barcelona, Spain ?Infectious Diseases Service, Idibell, Ciberes, Hospital Bellvitge, University of Barcelona, Barcelona, Spain.
Abstract
Seventy-one patients < 5 year-old who were hospitalized with invasive pneumococcal disease were studied in the period 8/2008-12/2009. The purpose was to determine the proportion of episodes that were coinfected with respiratory virus coinfection. Viral coinfection was common (44/71;62%) with rhinovirus and influenza virus being the most frequently detected. Highly invasive serotypes (1,5,7F,14,19A) were found in 31/71, of whom 15 had viral coinfection (15/31;48%). Viral detections occurred significantly more often in those episodes caused by non-highly invasive serotypes (29/40;72%), suggesting that a viral synergism could help those serotypes to make invasiveness more likely.
PMID:
22333697
[PubMed - as supplied by publisher]
Viral Coinfection in Children Less Than 5 Year-Old with Invasive Pneumococcal Disease.
Launes C, de-Sevilla MF, Selva L, Garcia-Garcia JJ, Pallares R, Mu?oz-Almagro C.
Source
*Infectious Diseases Unit, Department of Pediatrics, Hospital Sant Joan de Deu, Universitat de Barcelona, Spain ?Department of Molecular Microbiology, Hospital Sant Joan de Deu, Universitat de Barcelona, Spain ?Infectious Diseases Service, Idibell, Ciberes, Hospital Bellvitge, University of Barcelona, Barcelona, Spain.
Abstract
Seventy-one patients < 5 year-old who were hospitalized with invasive pneumococcal disease were studied in the period 8/2008-12/2009. The purpose was to determine the proportion of episodes that were coinfected with respiratory virus coinfection. Viral coinfection was common (44/71;62%) with rhinovirus and influenza virus being the most frequently detected. Highly invasive serotypes (1,5,7F,14,19A) were found in 31/71, of whom 15 had viral coinfection (15/31;48%). Viral detections occurred significantly more often in those episodes caused by non-highly invasive serotypes (29/40;72%), suggesting that a viral synergism could help those serotypes to make invasiveness more likely.
PMID:
22333697
[PubMed - as supplied by publisher]
