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Emerg Infect Dis . Fatal Infection in Ferrets after Ocular Inoculation with Highly Pathogenic Avian Influenza A(H5N1) Virus

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  • Emerg Infect Dis . Fatal Infection in Ferrets after Ocular Inoculation with Highly Pathogenic Avian Influenza A(H5N1) Virus

    Emerg Infect Dis


    . 2024 Jul;30(7):1484-1487.
    doi: 10.3201/eid3007.240520.
    Fatal Infection in Ferrets after Ocular Inoculation with Highly Pathogenic Avian Influenza A(H5N1) Virus

    Jessica A Belser, Xiangjie Sun, Joanna A Pulit-Penaloza, Taronna R MainesFree article Abstract

    Ocular inoculation of a clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) virus caused severe and fatal infection in ferrets. Virus was transmitted to ferrets in direct contact. The results highlight the potential capacity of these viruses to cause human disease after either respiratory or ocular exposure.

    Keywords: United States; avian influenza A(H5N1); ferret; highly pathogenic avian influenza; influenza; ocular; pathogenesis; transmission; viruses.

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