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J Assoc Med Microbiol Infect Dis Can
. 2023 Nov 29;8(3):187-191.
doi: 10.3138/jammi-2023-05-08. eCollection 2023 Nov. Highly pathogenic avian influenza: Unprecedented outbreaks in Canadian wildlife and domestic poultry
Christian Renaud 1 , Andrea Osborn 2 , Elizabeth Jane Parmley 3 , Todd F Hatchette 4 , J LeBlanc 4 , Jeffrey Scott Weese 5 , Vikram Misra 6 , Deborah Yamamura 7 , Sarah Forgie 8 , Shane Renwick 9 , Duncan Webster 10 , Samira Mubareka 11 ; AMMI Canada One Health working group
Affiliations
in English, French
Canada experienced a wave of HPAI H5N1 outbreaks in the spring of 2022 with millions of wild and farmed birds being infected. Seabird mortalities in Canada have been particularly severe on the Atlantic Coast over the summer of 2022. Over 7 million birds have been culled in Canada, and outbreaks continue to profoundly affect commercial bird farms across the world. This new H5N1 virus can and has infected multiple mammalian species, including skunks, foxes, bears, mink, seals, porpoises, sea lions, and dolphins. Viruses with mammalian adaptations such as the mutations PB2-E627K, E627V, and D701N were found in the brain of various carnivores in Europe and Canada. To date this specific clade of H5N1 virus has been identified in less than 10 humans. At the ground level, awareness should be raised among frontline practitioners most likely to encounter patients with HPAI.
Keywords: H5N1; One Health; avian flu; influenza; mammalian adaptation.
. 2023 Nov 29;8(3):187-191.
doi: 10.3138/jammi-2023-05-08. eCollection 2023 Nov. Highly pathogenic avian influenza: Unprecedented outbreaks in Canadian wildlife and domestic poultry
Christian Renaud 1 , Andrea Osborn 2 , Elizabeth Jane Parmley 3 , Todd F Hatchette 4 , J LeBlanc 4 , Jeffrey Scott Weese 5 , Vikram Misra 6 , Deborah Yamamura 7 , Sarah Forgie 8 , Shane Renwick 9 , Duncan Webster 10 , Samira Mubareka 11 ; AMMI Canada One Health working group
Affiliations
- PMID: 38058495
- PMCID: PMC10697099
- DOI: 10.3138/jammi-2023-05-08
in English, French
Canada experienced a wave of HPAI H5N1 outbreaks in the spring of 2022 with millions of wild and farmed birds being infected. Seabird mortalities in Canada have been particularly severe on the Atlantic Coast over the summer of 2022. Over 7 million birds have been culled in Canada, and outbreaks continue to profoundly affect commercial bird farms across the world. This new H5N1 virus can and has infected multiple mammalian species, including skunks, foxes, bears, mink, seals, porpoises, sea lions, and dolphins. Viruses with mammalian adaptations such as the mutations PB2-E627K, E627V, and D701N were found in the brain of various carnivores in Europe and Canada. To date this specific clade of H5N1 virus has been identified in less than 10 humans. At the ground level, awareness should be raised among frontline practitioners most likely to encounter patients with HPAI.
Keywords: H5N1; One Health; avian flu; influenza; mammalian adaptation.
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