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Microbiol Spectr
. 2023 Dec 13:e0302723.
doi: 10.1128/spectrum.03027-23. Online ahead of print. Lymphocyte and neutrophil count combined with intestinal bacteria abundance predict the severity of COVID-19
Liuying Chen # 1 , Zhongwei Yin # 2 , Dan Zhou 1 , Xin Li 3 , Cheng Yu 4 , Chang Luo 1 , Yu Jin 1 , Lei Zhang 1 , Jun Song 1 , Leo Rasche 5 , Hermann Einsele 5 , Lei Tu 1 , Xiang Zhou 5 , Tao Bai 1 , Xiaohua Hou 1
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The 2019 coronavirus disease (COVID-19) patients had a unique profile of gut bacteria. In this study, we characterized the intestinal bacteria in our COVID-19 cohorts and found that there was an increased incidence of severe cases in COVID-19 patients with decreased lymphocytes and increased neutrophils. Levels of lymphocytes and neutrophils and abundances of intestinal bacteria correlated with the severity of COVID-19.
Keywords: COVID-19; bacteria; lymphocytes; neutrophils.
. 2023 Dec 13:e0302723.
doi: 10.1128/spectrum.03027-23. Online ahead of print. Lymphocyte and neutrophil count combined with intestinal bacteria abundance predict the severity of COVID-19
Liuying Chen # 1 , Zhongwei Yin # 2 , Dan Zhou 1 , Xin Li 3 , Cheng Yu 4 , Chang Luo 1 , Yu Jin 1 , Lei Zhang 1 , Jun Song 1 , Leo Rasche 5 , Hermann Einsele 5 , Lei Tu 1 , Xiang Zhou 5 , Tao Bai 1 , Xiaohua Hou 1
Affiliations
- PMID: 38088542
- DOI: 10.1128/spectrum.03027-23
The 2019 coronavirus disease (COVID-19) patients had a unique profile of gut bacteria. In this study, we characterized the intestinal bacteria in our COVID-19 cohorts and found that there was an increased incidence of severe cases in COVID-19 patients with decreased lymphocytes and increased neutrophils. Levels of lymphocytes and neutrophils and abundances of intestinal bacteria correlated with the severity of COVID-19.
Keywords: COVID-19; bacteria; lymphocytes; neutrophils.