Microbes Infect . Application experience of a rapid nucleic acid detection system for COVID-19

[tetano]

Microbes Infect


. 2022 Jan 27;104945.
doi: 10.1016/j.micinf.2022.104945. Online ahead of print.
Application experience of a rapid nucleic acid detection system for COVID-19


Qing Ye ¹ , Dezhao Lu ² , Ting Zhang ³ , Jianhua Mao ⁴ , Shiqiang Shang ⁵



Affiliations

• PMID: 35093551
• DOI: 10.1016/j.micinf.2022.104945

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is raging worldwide. The COVID-19 outbreak caused severe threats to the life and health of all humans caused by SARS-CoV-2. Clinically, there is an urgent need for an in vitro diagnostic product to detect SARS-CoV-2 nucleic acid quickly. Under this background, commercial SARS-CoV-2 nucleic acid POCT products came into being. However, how to choose these products and how to use these products in a standardized way have brought new puzzles to clinical laboratories. This paper focuses on evaluating the performance of these commercial SARS-CoV-2 nucleic acid POCT products and helps the laboratory make the correct choice. At the same time, to standardize the use of this kind of product, this paper also puts forward corresponding suggestions from six elements of total quality management, namely, human, machine, material, method, environment, and measurement. In addition, this paper also puts forward some ideas on the future development direction of POCT products.

Keywords: COVID-19; SARS-CoV-2; point-of-care testing; quality control.