Diabetes Metab Syndr . Dyslipidemia is associated with severe coronavirus disease 2019 (COVID-19) infection

[tetano]

Diabetes Metab Syndr


. 2020 Aug 1;14(5):1463-1465.
doi: 10.1016/j.dsx.2020.07.054. Online ahead of print.
Dyslipidemia is associated with severe coronavirus disease 2019 (COVID-19) infection


Timotius Ivan Hariyanto ¹ , Andree Kurniawan ²



Affiliations

• PMID: 32771919
• DOI: 10.1016/j.dsx.2020.07.054

Abstract

Background and aims: The number of positive and death cases from coronavirus disease 2019 (COVID-19) is still increasing. The identification of risk factors for severe outcomes is important. Dyslipidemia has been shown as a long-known risk factor for cardiovascular disease. The aim of this study is to analyze the potential association between dyslipidemia and the severity of COVID-19 infection.
Methods: We systematically searched the PubMed database using specific keywords related to our aims until July 9th, 2020. All articles published on COVID-19 and dyslipidemia were retrieved. Statistical analysis was done using Review Manager 5.4 software.
Results: A total of 7 studies with a total of 6922 patients were included in our analysis. Our meta-analysis showed that dyslipidemia is associated with severe COVID-19 infections [RR 1.39 (95% CI 1.03-1.87), p = 0.03, I² = 57%, random-effect modelling].
Conclusion: Dyslipidemia increases the risk of the development of severe outcomes from COVID-19 infections. Patients with dyslipidemia should be monitored closely to minimize the risk of COVID-19.

Keywords: COVID-19; Coronavirus disease 2019; Dyslipidemia; Metabolic disease; Metabolic syndrome.