AJNR Am J Neuroradiol
. 2020 Jun 25.
doi: 10.3174/ajnr.A6675. Online ahead of print.
Anosmia in COVID-19 Associated With Injury to the Olfactory Bulbs Evident on MRI
M F V V Arag?o 1 2 , M C Leal 3 4 , O Q Cartaxo Filho 4 , T M Fonseca 4 , M M Valen?a 3
Affiliations
- PMID: 32586960
- DOI: 10.3174/ajnr.A6675
Abstract
Patients with coronavirus disease 2019 (COVID-19) may have symptoms of anosmia or partial loss of the sense of smell, often accompanied by changes in taste. We report 5 cases (3 with anosmia) of adult patients with COVID-19 in whom injury to the olfactory bulbs was interpreted as microbleeding or abnormal enhancement on MR imaging. The patients had persistent headache (n = 4) or motor deficits (n = 1). This olfactory bulb injury may be the mechanism by which the Severe Acute Respiratory Syndrome coronavirus 2 causes olfactory dysfunction.