Tweet
Jpn J Radiol. 2020 Mar 30. doi: 10.1007/s11604-020-00958-w. [Epub ahead of print]
Diagnostic performance of chest CT to differentiate COVID-19 pneumonia in non-high-epidemic area in Japan.
Himoto Y1, Sakata A2, Kirita M2, Hiroi T2, Kobayashi KI3, Kubo K3, Kim H2, Nishimoto A2, Maeda C2, Kawamura A2, Komiya N3, Umeoka S2.
Author information
Abstract
PURPOSE:
To evaluate the diagnostic performance of chest CT to differentiate coronavirus disease 2019 (COVID-19) pneumonia in non-high-epidemic area in Japan.
MATERIALS AND METHODS:
This retrospective study included 21 patients clinically suspected COVID-19 pneumonia and underwent chest CT more than 3 days after the symptom onset: six patients confirmed COVID-19 pneumonia by real-time reverse-transcription polymerase chain reaction (RT-PCR) and 15 patients proved uninfected. Using a Likert scale and its receiver operating characteristic curve analysis, two radiologists (R1/R2) evaluated the diagnostic performance of the five CT criteria: (1) ground glass opacity (GGO)-predominant lesions, (2) GGO- and peripheral-predominant lesions, (3) bilateral GGO-predominant lesions; (4) bilateral GGO- and peripheral-predominant lesions, and (5) bilateral GGO- and peripheral-predominant lesions without nodules, airway abnormalities, pleural effusion, and mediastinal lymphadenopathy.
RESULTS:
All patients confirmed COVID-19 pneumonia had bilateral GGO- and peripheral-predominant lesions without airway abnormalities, mediastinal lymphadenopathy, and pleural effusion. The five CT criteria showed moderate to excellent diagnostic performance with area under the curves (AUCs) ranging 0.77-0.88 for R1 and 0.78-0.92 for R2. The criterion (e) showed the highest AUC.
CONCLUSION:
Chest CT would play a supplemental role to differentiate COVID-19 pneumonia from other respiratory diseases presenting with similar symptoms in a clinical setting.
KEYWORDS:
COVID-19; CT criteria; Chest CT; Diagnostic performance
PMID:32232648DOI:10.1007/s11604-020-00958-w