J Med Virol . Persistently positive SARS-CoV-2 specific IgM during one-year follow-up - FluTrackers News and Information

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J Med Virol . Persistently positive SARS-CoV-2 specific IgM during one-year follow-up

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tetano

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J Med Virol . Persistently positive SARS-CoV-2 specific IgM during one-year follow-up

May 5, 2022, 04:11 AM

J Med Virol

. 2022 May 3.
doi: 10.1002/jmv.27822. Online ahead of print.
Persistently positive SARS-CoV-2 specific IgM during one-year follow-up

Marcela Helena Gambim Fonseca¹, Maria Francilene Souza Silva¹, Ana Carolina Matias Dinelly Pinto¹, Amanda Campelo Lima de Melo¹, Fátima de Cássia Evangelista de Oliveira¹, Fernanda Montenegro de Carvalho Araújo¹, Luiz Odorico Monteiro de Andrade¹

Affiliations
PMID: 35505640

DOI: 10.1002/jmv.27822

Abstract

IgM antibodies typically appear in the early stage of infection and have a short maintenance time, so IgM is frequently used as a diagnostic criterion for acute or recent disease [1]. However, unconventional IgM specific responses have been described in SARS-COV-2 infection, raising doubts about the use of IgM as a biomarker for COVID-19 and the role of this antibody in immunity to SARS-CoV-2 [1,2]. This article is protected by copyright. All rights reserved.

Keywords: Coronavirus; Humoral immuity; Immune responses; Immunoglobin; Virus classification.

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