Mem Inst Oswaldo Cruz . Low risk of serological cross-reactivity between dengue and COVID-19 - FluTrackers News and Information

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Mem Inst Oswaldo Cruz . Low risk of serological cross-reactivity between dengue and COVID-19

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tetano

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Mem Inst Oswaldo Cruz . Low risk of serological cross-reactivity between dengue and COVID-19

August 20, 2020, 02:05 AM

Mem Inst Oswaldo Cruz

. 2020;115:e200225.
doi: 10.1590/0074-02760200225. Epub 2020 Aug 14.
Low risk of serological cross-reactivity between dengue and COVID-19

Michele Spinicci¹, Alessandro Bartoloni¹, Antonia Mantella¹, Lorenzo Zammarchi¹, Gian Maria Rossolini¹, Alberto Antonelli¹

Affiliations
PMID: 32813814

DOI: 10.1590/0074-02760200225

Abstract

In the near future, the overlap of Coronavirus disease 2019 (COVID-19) and dengue epidemics is a concrete threat in tropical regions. Co-epidemics of COVID-19 and dengue could be an overwhelming challenge for health systems in low- and middle-income countries. In this work, we investigated potential serological cross-reactions between COVID-19 and dengue patients. Among 32 COVID-19 positive sera, no positive Dengue virus (DENV) IgG/IgM results were observed. On the other hand, one false-positive result was observed among 44 DENV-positive sera tested for COVID-19 antibodies with each of the two rapid tests used. Further data on accuracy of COVID-19 diagnostic test are urgently warranted.

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