Ecohealth. 2010 May 11. [Epub ahead of print]
Wild Bird's-eye View of Influenza Virus A(H1N1) Phylogenetic Evolution.
Piaggio AJ, Clark L, Franklin AB, Kolokotronis SO.
National Wildlife Research Center, United States Department of Agriculture, Wildlife Services, 4101 LaPorte Avenue, Fort Collins, CO, 80521, USA, Toni.J.Piaggio@aphis.usda.gov.
Abstract
Wild bird fecal samples collected and characterized by the USDA as part of a national surveillance effort were sequenced to study the genetic relatedness of avian, swine, and human H1 and N1 subtypes. Our results find that the 2009 H1N1 human outbreak is closely related to swine virus, but falls into different clades in the H1 and N1 trees. Further, there is evidence of multiple viral genetic exchanges between birds and swine. Ongoing research across host species contributes to an understanding of the circulation of influenza viruses.
PMID: 20458519 [PubMed - as supplied by publisher]
Wild Bird's-eye View of Influenza Virus A(H1N1) Phylogenetic Evolution.
Piaggio AJ, Clark L, Franklin AB, Kolokotronis SO.
National Wildlife Research Center, United States Department of Agriculture, Wildlife Services, 4101 LaPorte Avenue, Fort Collins, CO, 80521, USA, Toni.J.Piaggio@aphis.usda.gov.
Abstract
Wild bird fecal samples collected and characterized by the USDA as part of a national surveillance effort were sequenced to study the genetic relatedness of avian, swine, and human H1 and N1 subtypes. Our results find that the 2009 H1N1 human outbreak is closely related to swine virus, but falls into different clades in the H1 and N1 trees. Further, there is evidence of multiple viral genetic exchanges between birds and swine. Ongoing research across host species contributes to an understanding of the circulation of influenza viruses.
PMID: 20458519 [PubMed - as supplied by publisher]