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J Virol Methods. A rapid test for the detection of influenza A virus including pandemic influenza A/H1N1 2009.

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  • J Virol Methods. A rapid test for the detection of influenza A virus including pandemic influenza A/H1N1 2009.

    A rapid test for the detection of influenza A virus including pandemic influenza A/H1N1 2009. (J Virol Methods., abstract, edited)

    8. J Virol Methods. 2010 Feb 5. [Epub ahead of print]

    A rapid test for the detection of influenza A virus including pandemic influenza A/H1N1 2009.

    Chen Y, Xu F, Gui X, Yang K, Wu X, Zheng Q, Ge S, Yuan Q, Yeo AE, Zhang J, Guan Y, Chen H, Xia N. - National Institute of Diagnostics and Vaccine Development in infectious diseases, School of Life Science, Xiamen University, Xiamen, China.


    A new rapid diagnostic test for detection of influenza A virus was evaluated with four sets of experiments: first, a comparison with a commercial diagnostic kit against a panel of virus strains was conducted; second, the kit was tested against a collection of 40 strains of influenza A virus isolated from five different host species and 26 strains of other respiratory viruses used as controls; third, the kit was tested against specimens collected in the field obtained from human and chicken; and fourth, the kit was tested against the novel pandemic influenza A/H1N1 2009 clinical specimens obtained from admitted to hospital patients. The test kit displayed a sensitivity of 88% for both human specimens and avian specimens. The corresponding specificity was 99.3% for human specimens and 96.5% for avian specimens. This test kit may be useful for rapid diagnosis of influenza A virus.

    Copyright ? 2010. Published by Elsevier B.V.

    PMID: 20144656 [PubMed - as supplied by publisher]
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