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Int J Infect Dis. 2019 Mar 26. pii: S1201-9712(19)30156-0. doi: 10.1016/j.ijid.2019.03.027. [Epub ahead of print]
Contribution of the FilmArray respiratory panel in the management of adult and pediatric patients attending the emergency room during 2015-2016 influenza epidemics: an interventional study.
Busson L1, Bartiaux M2, Brahim S2, Konopnicki D3, Dauby N3, G?rard M3, De Backer P4, Van Vaerenbergh K4, Mahadeb B1, Mekkaoui L1, De Foor M1, Wautier M5, Vandenberg O6, Mols P2, Levy J4, Hallin M1.
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Abstract
AIM:
To evaluate the contribution of a multiplex PCR for respiratory viruses on antibiotic and antiviral prescription, ancillary test prescription, admission and length of stay of patients.
METHODS:
Two hundred ninety-one adult and pediatric patients visiting the emergency department during the 2015-2016 influenza epidemic were prospectively included and immediately tested 24/7 using the FilmArray Respiratory Panel. The results were communicated to the practitioner in charge as soon as they became available. Clinical and biological data were gathered and analyzed.
FINDINGS:
Results from the FilmArray Respiratory Panel do not appear to impact admission or antibiotic prescription, with the exception of a lower admission rate for children who tested positive for influenza B. Parameters that account for the clinical decisions evaluated are CRP level, white blood cell count, suspected or proven bacterial infection and, for adult patients only, signs of respiratory distress. Length of stay is also not significantly different between patients with a positive and a negative result. A rapid influenza test result permits a more appropriate prescription of oseltamivir.
Copyright ? 2019. Published by Elsevier Ltd.
KEYWORDS:
FilmArray Respiratory Panel; antibiotic; antiviral length of stay; influenza; patient management; respiratory viruses
PMID: 30926539 DOI: 10.1016/j.ijid.2019.03.027
Free full text
Contribution of the FilmArray respiratory panel in the management of adult and pediatric patients attending the emergency room during 2015-2016 influenza epidemics: an interventional study.
Busson L1, Bartiaux M2, Brahim S2, Konopnicki D3, Dauby N3, G?rard M3, De Backer P4, Van Vaerenbergh K4, Mahadeb B1, Mekkaoui L1, De Foor M1, Wautier M5, Vandenberg O6, Mols P2, Levy J4, Hallin M1.
Author information
Abstract
AIM:
To evaluate the contribution of a multiplex PCR for respiratory viruses on antibiotic and antiviral prescription, ancillary test prescription, admission and length of stay of patients.
METHODS:
Two hundred ninety-one adult and pediatric patients visiting the emergency department during the 2015-2016 influenza epidemic were prospectively included and immediately tested 24/7 using the FilmArray Respiratory Panel. The results were communicated to the practitioner in charge as soon as they became available. Clinical and biological data were gathered and analyzed.
FINDINGS:
Results from the FilmArray Respiratory Panel do not appear to impact admission or antibiotic prescription, with the exception of a lower admission rate for children who tested positive for influenza B. Parameters that account for the clinical decisions evaluated are CRP level, white blood cell count, suspected or proven bacterial infection and, for adult patients only, signs of respiratory distress. Length of stay is also not significantly different between patients with a positive and a negative result. A rapid influenza test result permits a more appropriate prescription of oseltamivir.
Copyright ? 2019. Published by Elsevier Ltd.
KEYWORDS:
FilmArray Respiratory Panel; antibiotic; antiviral length of stay; influenza; patient management; respiratory viruses
PMID: 30926539 DOI: 10.1016/j.ijid.2019.03.027
Free full text