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Zhonghua Yi Xue Za Zhi. 2010 Sep;90(34):2392-2395.
[Risk factors of novel severe influenza A(H1N1) with concurrent adult respiratory distress syndrome.]
[Article in Chinese]
Dai B, Kang J, Wang ZF, Kong DL, Tan W, Zhao HW.
Department of Respiratory Medicine, First Affiliated Hospital, China Medical University, Shenyang 110001, China.
Abstract
OBJECTIVE: To analyze the risk factors of novel severe influenza A (H1N1) with concurrent adult respiratory distress syndrome (ARDS).
METHODS: A multivariable Logistic regression analysis was conducted for ARDS risk factors in controlled clinical trials for comparing the clinical features between the ARDS and non-ARDS groups and comparing ARDS patients' lymphocyte counts and T lymphocyte subsets between the smoking and non-smoking groups through a retrospective analysis of 92 novel influenza A (H1N1) patients who admitted to our hospital from October 2009 to January 2010.
RESULTS: Through a single factor analysis between ARDS and non-ARDS groups, the comparisons in the factors including smoking (17 cases vs 11 cases), T lymphocyte subsets, lactate dehydrogenase (LDH), initial treatment point of oseltamivir and initial oxygen flow greater than 2 L/min (28 cases vs 18 cases) had statistically significant differences (all P < 0.05). The comparison in T lymphocyte subsets had statistically significant difference between the smoking and non-smoking groups in ARDS patients (all P < 0.05). The multivariable Logistic regression analysis showed that smoking (P = 0.027, OR = 8.05, 95%CI: 1.28 - 50.80) and initial oxygen flow greater than 2 L/min (P = 0.010, OR = 16.70, 95%CI: 3.29 - 84.84) were relevant to the incidence of ARDS in novel influenza A (H1N1) patients.
CONCLUSION: Smoking and initial oxygen flow greater than 2 L/min were the risk factors of novel severe influenza A (H1N1) with concurrent ARDS.
PMID: 21092507 [PubMed - as supplied by publisher]
[Risk factors of novel severe influenza A(H1N1) with concurrent adult respiratory distress syndrome.]
[Article in Chinese]
Dai B, Kang J, Wang ZF, Kong DL, Tan W, Zhao HW.
Department of Respiratory Medicine, First Affiliated Hospital, China Medical University, Shenyang 110001, China.
Abstract
OBJECTIVE: To analyze the risk factors of novel severe influenza A (H1N1) with concurrent adult respiratory distress syndrome (ARDS).
METHODS: A multivariable Logistic regression analysis was conducted for ARDS risk factors in controlled clinical trials for comparing the clinical features between the ARDS and non-ARDS groups and comparing ARDS patients' lymphocyte counts and T lymphocyte subsets between the smoking and non-smoking groups through a retrospective analysis of 92 novel influenza A (H1N1) patients who admitted to our hospital from October 2009 to January 2010.
RESULTS: Through a single factor analysis between ARDS and non-ARDS groups, the comparisons in the factors including smoking (17 cases vs 11 cases), T lymphocyte subsets, lactate dehydrogenase (LDH), initial treatment point of oseltamivir and initial oxygen flow greater than 2 L/min (28 cases vs 18 cases) had statistically significant differences (all P < 0.05). The comparison in T lymphocyte subsets had statistically significant difference between the smoking and non-smoking groups in ARDS patients (all P < 0.05). The multivariable Logistic regression analysis showed that smoking (P = 0.027, OR = 8.05, 95%CI: 1.28 - 50.80) and initial oxygen flow greater than 2 L/min (P = 0.010, OR = 16.70, 95%CI: 3.29 - 84.84) were relevant to the incidence of ARDS in novel influenza A (H1N1) patients.
CONCLUSION: Smoking and initial oxygen flow greater than 2 L/min were the risk factors of novel severe influenza A (H1N1) with concurrent ARDS.
PMID: 21092507 [PubMed - as supplied by publisher]
