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AIDS. 2010 Jul 15. [Epub ahead of print]
Pandemic flu: a comparative evaluation of clinical, laboratory, and radiographic findings in HIV-positive and negative children.
Antonietta G, Andrea LV, Teresa RM, Rosaria PM, Alessandro B, Eliana R, Antonio C, Alfredo G.
aDepartment of Pediatrics, University Federico II, Italy bSantobono Pediatric Hospital, Naples, Italy.
Abstract
Eleven HIV-infected and 30 otherwise healthy children hospitalized for H1N1 influenza were studied. Leukopenia was recorded in 64% of HIV-infected and in 20% of healthy children (P = 0.01). Chest radiograph was abnormal in 18 (46%) children. Interstitial pneumonia was more frequent in HIV-positive children and consolidation was more frequent in HIV-negative children. Although the duration of symptoms and hospital stay was significantly longer in HIV-negative than in HIV-positive children, only 37% of HIV-negative children and 91% of HIV-positive received oseltamivir. The H1N1 influenza attack rate was very high (20%) in HIV-infected children, but it consistently ran a mild course.
PMID: 20639725 [PubMed - as supplied by publisher]
Pandemic flu: a comparative evaluation of clinical, laboratory, and radiographic findings in HIV-positive and negative children.
Antonietta G, Andrea LV, Teresa RM, Rosaria PM, Alessandro B, Eliana R, Antonio C, Alfredo G.
aDepartment of Pediatrics, University Federico II, Italy bSantobono Pediatric Hospital, Naples, Italy.
Abstract
Eleven HIV-infected and 30 otherwise healthy children hospitalized for H1N1 influenza were studied. Leukopenia was recorded in 64% of HIV-infected and in 20% of healthy children (P = 0.01). Chest radiograph was abnormal in 18 (46%) children. Interstitial pneumonia was more frequent in HIV-positive children and consolidation was more frequent in HIV-negative children. Although the duration of symptoms and hospital stay was significantly longer in HIV-negative than in HIV-positive children, only 37% of HIV-negative children and 91% of HIV-positive received oseltamivir. The H1N1 influenza attack rate was very high (20%) in HIV-infected children, but it consistently ran a mild course.
PMID: 20639725 [PubMed - as supplied by publisher]
