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Clinical features of H1N1 2009 infection in critically ill immunocompromised patients

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  • Clinical features of H1N1 2009 infection in critically ill immunocompromised patients

    Critical Care
    Volume 14
    Issue 2
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    Commentary
    Clinical features of H1N1 2009 infection in critically ill immunocompromised patients

    Laurent Camous1,2, Virginie Lemiale1,2, Emmanuel Canet1,2, Adeline Max1,2, David Schnell1,2, Jerome Le Goff2,3, Antoine Rabbat4, Benoit Schlemmer1,2 and ?lie Azoulay1,2 email

    1 Medical Intensive Care Unit, Saint-Louis University Hospital, APHP, 1 Avenue Claude Vellefaux, 75010 Paris, France

    2 Paris-7 Paris-Diderot University, UFR de M?decine, 1 Avenue Claude Vellefaux, 75010 Paris, France

    3 Virology Unit, Saint-Louis University Hospital, APHP, 1 Avenue Claude Vellefaux, 75010 Paris, France

    4 Medical Intensive Care Unit, H?tel Dieu University Hospital, APHP, 1 Avenue Claude Vellefaux, 75010 Paris, France

    Critical Care 2010, 14:139doi:10.1186/cc8927
    Published: 14 April 2010
    Abstract

    Seasonal influenza virus has been described as an emerging and severe pathogen in immunocompromised hosts. Since the beginning of the 2009 influenza A novel H1N1 pandemic, several series have described the clinical course of the disease in various populations. We report the clinical course of H1N1 2009 infection in 10 immunocompromised patients. Half of the patients received long-term steroid therapy. Disease was characterized by a clinical picture similar to that of non-immunocompromised patients but with prolonged course and higher mortality.

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