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Open Forum Infect Dis. 2014 Oct 10;1(3):ofu082. doi: 10.1093/ofid/ofu082. eCollection 2014.
Seroincidence of Influenza Among HIV-infected and HIV-uninfected Men During the 2009 H1N1 Influenza Pandemic, Bangkok, Thailand.
Garg S1, Olsen SJ2, Fernandez S3, Muangchana C4, Rungrojcharoenkit K3, Prapasiri P5, Katz JM6, Curlin ME7, Gibbons RV3, Holtz TH7, Chitwarakorn A8, Dawood FS6.
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Abstract
Among 368 Thai men who have sex with men with paired serum samples collected before and during the 2009 H1N1 influenza pandemic, we determined influenza A (H1N1)pdm09 seroconversion rates (≥4-fold rise in antibody titers by hemagglutination inhibition or microneutralization assays). Overall, 66 of 232 (28%) participants seroconverted after the first year of A(H1N1)pdm09 activity, and 83 of 234 (35%) participants seroconverted after the second year. Influenza A(H1N1)pdm09 seroconversion did not differ between human immunodeficiency virus (HIV)-infected (55 of 2157 [35%]) and HIV-uninfected (71 of 2211 [34%]) participants (P = .78). Influenza A(H1N1)pdm09 seroconversion occurred in approximately one third of our Thai study population and was similar among HIV-infected and HIV-uninfected participants.
KEYWORDS:
A(H1N1)pdm09; HIV; Thailand; influenza; pandemic; serology
PMID: 25734157 [PubMed] PMCID: PMC4324228 Free PMC Article
Seroincidence of Influenza Among HIV-infected and HIV-uninfected Men During the 2009 H1N1 Influenza Pandemic, Bangkok, Thailand.
Garg S1, Olsen SJ2, Fernandez S3, Muangchana C4, Rungrojcharoenkit K3, Prapasiri P5, Katz JM6, Curlin ME7, Gibbons RV3, Holtz TH7, Chitwarakorn A8, Dawood FS6.
Author information
Abstract
Among 368 Thai men who have sex with men with paired serum samples collected before and during the 2009 H1N1 influenza pandemic, we determined influenza A (H1N1)pdm09 seroconversion rates (≥4-fold rise in antibody titers by hemagglutination inhibition or microneutralization assays). Overall, 66 of 232 (28%) participants seroconverted after the first year of A(H1N1)pdm09 activity, and 83 of 234 (35%) participants seroconverted after the second year. Influenza A(H1N1)pdm09 seroconversion did not differ between human immunodeficiency virus (HIV)-infected (55 of 2157 [35%]) and HIV-uninfected (71 of 2211 [34%]) participants (P = .78). Influenza A(H1N1)pdm09 seroconversion occurred in approximately one third of our Thai study population and was similar among HIV-infected and HIV-uninfected participants.
KEYWORDS:
A(H1N1)pdm09; HIV; Thailand; influenza; pandemic; serology
PMID: 25734157 [PubMed] PMCID: PMC4324228 Free PMC Article