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J Clin Virol. 2014 Jul 16. pii: S1386-6532(14)00267-4. doi: 10.1016/j.jcv.2014.07.004. [Epub ahead of print]
Prolonged shedding of pandemic influenza A (H1N1) 2009 virus in a pancreas-after-kidney transplant recipient.
Bruminhent J1, Deziel PJ2, Wotton JT3, Binnicker MJ4, Razonable RR5.
Author information
Abstract
Prolonged shedding of influenza virus has been reported in immunocompromised patients. Delayed viral clearance may contribute to antiviral resistance and nosocomial transmission. We report a case of a pancreas-after-kidney transplant recipient who had detectable pandemic influenza A virus for 12 months. Pyrosequencing analysis detected the H275Y mutation, which is associated with resistance to oseltamivir.
Copyright ? 2014 Elsevier B.V. All rights reserved.
KEYWORDS:
Immunocompromised; Influenza; Oseltamivir; Shedding; Transmission; Transplant
PMID:
25081940
[PubMed - as supplied by publisher]
Prolonged shedding of pandemic influenza A (H1N1) 2009 virus in a pancreas-after-kidney transplant recipient.
Bruminhent J1, Deziel PJ2, Wotton JT3, Binnicker MJ4, Razonable RR5.
Author information
Abstract
Prolonged shedding of influenza virus has been reported in immunocompromised patients. Delayed viral clearance may contribute to antiviral resistance and nosocomial transmission. We report a case of a pancreas-after-kidney transplant recipient who had detectable pandemic influenza A virus for 12 months. Pyrosequencing analysis detected the H275Y mutation, which is associated with resistance to oseltamivir.
Copyright ? 2014 Elsevier B.V. All rights reserved.
KEYWORDS:
Immunocompromised; Influenza; Oseltamivir; Shedding; Transmission; Transplant
PMID:
25081940
[PubMed - as supplied by publisher]
