Epidemiol Infect. 2014 Aug 1:1-10. [Epub ahead of print]
Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK.
Nyland GA1, McKENZIE BC1, Myles PR1, Semple MG2, Lim WS3, Openshaw PJ4, Read RC5, Taylor BL6, Brett SJ7, McMENAMIN J8, Enstone JE1, Bannister B9, Nicholson KG10, Nguyen-VAN-Tam JS1.
Author information
Abstract
SUMMARY Data were extracted from the case records of UK patients admitted with laboratory-confirmed influenza A(H1N1)pdm09. White and non-White patients were characterized by age, sex, socioeconomic status, pandemic wave and indicators of pre-morbid health status. Logistic regression examined differences by ethnicity in patient characteristics, care pathway and clinical outcomes; multivariable models controlled for potential confounders. Whites (n = 630) and non-Whites (n = 510) differed by age, socioeconomic status, pandemic wave of admission, pregnancy, recorded obesity, previous and current smoking, and presence of chronic obstructive pulmonary disease. After adjustment for a priori confounders non-Whites were less likely to have received pre-admission antibiotics [adjusted odds ratio (aOR) 0?43, 95% confidence interval (CI) 0?28-0?68, P < 0?001) but more likely to receive antiviral drugs as in-patients (aOR 1?53, 95% CI 1?08-2?18, P = 0?018). However, there were no significant differences by ethnicity in delayed admission, severity at presentation for admission, or likelihood of severe outcome.
PMID:
25084481
[PubMed - as supplied by publisher]
Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK.
Nyland GA1, McKENZIE BC1, Myles PR1, Semple MG2, Lim WS3, Openshaw PJ4, Read RC5, Taylor BL6, Brett SJ7, McMENAMIN J8, Enstone JE1, Bannister B9, Nicholson KG10, Nguyen-VAN-Tam JS1.
Author information
Abstract
SUMMARY Data were extracted from the case records of UK patients admitted with laboratory-confirmed influenza A(H1N1)pdm09. White and non-White patients were characterized by age, sex, socioeconomic status, pandemic wave and indicators of pre-morbid health status. Logistic regression examined differences by ethnicity in patient characteristics, care pathway and clinical outcomes; multivariable models controlled for potential confounders. Whites (n = 630) and non-Whites (n = 510) differed by age, socioeconomic status, pandemic wave of admission, pregnancy, recorded obesity, previous and current smoking, and presence of chronic obstructive pulmonary disease. After adjustment for a priori confounders non-Whites were less likely to have received pre-admission antibiotics [adjusted odds ratio (aOR) 0?43, 95% confidence interval (CI) 0?28-0?68, P < 0?001) but more likely to receive antiviral drugs as in-patients (aOR 1?53, 95% CI 1?08-2?18, P = 0?018). However, there were no significant differences by ethnicity in delayed admission, severity at presentation for admission, or likelihood of severe outcome.
PMID:
25084481
[PubMed - as supplied by publisher]