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Pediatr Infect Dis J. 2013 Jul 31. [Epub ahead of print]
Prospective Cohort Study Comparing Seasonal and H1N1(2009)-Pandemic Influenza Virus Illnesses in HIV-Infected Children During 2009.
Madhi SA, Kuwanda L, Venter M, Violari A.
Source
1National Institute of Communicable Diseases- Division of National Health Laboratory Service, South Africa 2 Department of Science and Technology/ National Research Foundation: Vaccine Preventable Diseases, University of the Witwatersrand, South Africa 3 Medical Research Council: Respiratory & Meningeal Pathogens Research Unit, University of the Witwatersrand, South Africa 4Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
Abstract
A cohort of 410 young HIV-infected children was prospectively investigated for seasonal and A(H1N1p)2009 influenza virus illness during 2009. The incidence of confirmed illness due to seasonal influenza was three-fold greater than A(H1N1p)2009 (0.7 vs. 0.2 per 100 child-weeks, respectively; p=0.0001) and the clinical presentations were similar. Illnesses due to seasonal and A(H1N1p)2009 influenza were self-limiting without neuraminidase inhibitor therapy.
PMID:
23907261
[PubMed - as supplied by publisher]
Prospective Cohort Study Comparing Seasonal and H1N1(2009)-Pandemic Influenza Virus Illnesses in HIV-Infected Children During 2009.
Madhi SA, Kuwanda L, Venter M, Violari A.
Source
1National Institute of Communicable Diseases- Division of National Health Laboratory Service, South Africa 2 Department of Science and Technology/ National Research Foundation: Vaccine Preventable Diseases, University of the Witwatersrand, South Africa 3 Medical Research Council: Respiratory & Meningeal Pathogens Research Unit, University of the Witwatersrand, South Africa 4Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
Abstract
A cohort of 410 young HIV-infected children was prospectively investigated for seasonal and A(H1N1p)2009 influenza virus illness during 2009. The incidence of confirmed illness due to seasonal influenza was three-fold greater than A(H1N1p)2009 (0.7 vs. 0.2 per 100 child-weeks, respectively; p=0.0001) and the clinical presentations were similar. Illnesses due to seasonal and A(H1N1p)2009 influenza were self-limiting without neuraminidase inhibitor therapy.
PMID:
23907261
[PubMed - as supplied by publisher]
