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Description of patients with confirmed influenza A(H1N1)pdm09 admitted to an intensive care unit and identification of severity risk factors

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  • Description of patients with confirmed influenza A(H1N1)pdm09 admitted to an intensive care unit and identification of severity risk factors

    Med Mal Infect. 2013 Feb 28. pii: S0399-077X(13)00032-2. doi: 10.1016/j.medmal.2013.01.016. [Epub ahead of print]
    [Description of patients with confirmed influenza A(H1N1)pdm09 admitted to an intensive care unit and identification of severity risk factors.]
    [Article in French]
    Payet C, Lutringer-Magnin D, Cassier P, Lina B, Argaud L, Allaouchiche B, Vanhems P.
    Source

    Unit? ?pid?miologie et biomarqueurs de l'infection, service d'hygi?ne, ?pid?miologie et pr?vention, hospices civils de Lyon, 69437 Lyon cedex 03, France; CNRS, UMR5558, laboratoire de biom?trie et biologie ?volutive, ?quipe ?pid?miologie et sant? publique, universit? de Lyon, universit? Lyon 1, 69100 Villeurbanne, France. Electronic address: cecile.payet@univ-lyon1.fr.
    Abstract
    OBJECTIVE:

    The authors had for objective to describe patients with confirmed influenza A(H1N1)pdm09 admitted to an intensive care unit (ICU) in a university hospital and to identify risk factors correlated with the severity of the disease.
    DESIGN:

    A prospective study was conducted in an university hospital during the A(H1N1)pdm09 influenza pandemic. Severe laboratory confirmed cases (admitted to an ICU) were described and compared with non-severe confirmed cases (not admitted to an ICU).
    RESULTS:

    Sixty-nine patients were included; 36 (52%) were 15 to 44 years of age. Sixteen (23%) cases were defined as severe, ten of these (63%) concerned patients 45 to 64 years of age. The independent factors associated with severity were: a history of heart disease, obesity, and tobacco abuse.
    CONCLUSIONS:

    This work reinforces the need to identify and protect groups at risk of severe outcomes.

    Copyright ? 2013 Elsevier Masson SAS. All rights reserved.

    PMID:
    23453670
    [PubMed - as supplied by publisher]

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