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Pediatr Infect Dis J. 2012 Nov 28. [Epub ahead of print]
Comparative Analysis of Clinical Characteristics of Pandemic Influenza A/H1N1 and Seasonal Influenza A Infections in Hospitalized Children.
Heininger U, Baer G, Ryser AJ, Li Y.
Source
Division of Pediatric Infectious Diseases, University Children's Hospital, University of Basel, Switzerland.
Abstract
Pandemic influenza A/H1N1 (piA) caused significant morbidity and mortality worldwide. We compared characteristics of piA (2009/10) to those of seasonal influenza A (siA; 2007/08/09) in 134 (piA/siA: N=55/79) hospitalized patients <18 years of age. Chronic disease was present in 25%/33%. Most common symptoms were fever (87%/94%), cough (78%/86%), rhinitis (76%/76%) and pharyngitis (67%/68%). Croup syndrome (15%/3%), conjunctivitis (31%/10%) and febrile seizures (26%/13%) were more frequent in piA; 64%/53% patients had >1 complication and 5 (3/2) were admitted to ICU. Oseltamivir use was 20%/0%. Severity of pandemic influenza disease was not different compared with seasonal influenza A in preceding years.
PMID:
23190773
[PubMed - as supplied by publisher]
Comparative Analysis of Clinical Characteristics of Pandemic Influenza A/H1N1 and Seasonal Influenza A Infections in Hospitalized Children.
Heininger U, Baer G, Ryser AJ, Li Y.
Source
Division of Pediatric Infectious Diseases, University Children's Hospital, University of Basel, Switzerland.
Abstract
Pandemic influenza A/H1N1 (piA) caused significant morbidity and mortality worldwide. We compared characteristics of piA (2009/10) to those of seasonal influenza A (siA; 2007/08/09) in 134 (piA/siA: N=55/79) hospitalized patients <18 years of age. Chronic disease was present in 25%/33%. Most common symptoms were fever (87%/94%), cough (78%/86%), rhinitis (76%/76%) and pharyngitis (67%/68%). Croup syndrome (15%/3%), conjunctivitis (31%/10%) and febrile seizures (26%/13%) were more frequent in piA; 64%/53% patients had >1 complication and 5 (3/2) were admitted to ICU. Oseltamivir use was 20%/0%. Severity of pandemic influenza disease was not different compared with seasonal influenza A in preceding years.
PMID:
23190773
[PubMed - as supplied by publisher]
