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Acute kidney injury in critically ill a(h1n1)-infected patients: A study of the prognoses

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  • Acute kidney injury in critically ill a(h1n1)-infected patients: A study of the prognoses

    ACUTE KIDNEY INJURY IN CRITICALLY ILL A(H1N1)-INFECTED PATIENTS: A STUDY OF THE PROGNOSES

    Anis Chaari MD,
    Hssan Dammak MD,
    Kamilia Chtara MD,
    Mabrouk Bahloul MD,
    Mounir Bouaziz MD

    Article first published online: 2 AUG 2011

    DOI: 10.1111/j.1755-6686.2011.00224.x

    ? 2011 European Dialysis and Transplant Nurses Association/European Renal Care Association

    Issue
    Journal of Renal Care
    Journal of Renal Care

    Volume 37, Issue 3, pages 128?133, September 2011

    Additional Information(Show All)

    How to CiteAuthor InformationPublication History

    Chaari A., Dammak H., Chtara K., Bahloul M., Bouaziz M. (2011). Acute kidney injury in critically ill A(H1N1)-infected patients: a study of the prognoses. Journal of Renal Care 37(3), 128-133.


    SUMMARY

    Purpose: to identify factors correlated with poor outcome and factors correlated with acute kidney injury (AKI) onset in critically A(H1N1) infected patients.

    Methods: All patients admitted for respiratory distress due to a confirmed infection by A(H1N1) virus were included retrospectively.

    Results: Thirty-four patients were included. Mean age was 37.3 ? 20.8 years. Independent factors correlated to mortality in multivariate analysis were shock [OR = 32.52, CI95% (1.29?816.3); p = 0.034], AKI [OR = 31.12, CI95% (1.3?746.5); p = 0.034] and hyperglycaemia over than 5.7 mmol/l on admission [OR = 74, CI95% (1.01?5495); p = 0.049]. Only age over 30 years was identified as an independent factor correlated with the onset of AKI [OR = 18, CI95% (1.04-312.41); p = 0.047] in multivariate analysis.

    Conclusion: AKI, as well as hypotension, is an independent factor correlated with mortality. Its onset is usually linked to multi-organ failure. Advanced age is an important risk factor for renal dysfunction in this group of patients.

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