Heart Lung. 2011 Mar 14. [Epub ahead of print]
Fulminant myocarditis associated with novel H1N1 influenza A.
Khouzam RN, Parizianu C, Hafiz AM, Chawla S, Schwartz R.
Division of Cardiology, Winthrop University Hospital, Mineola, New York.
Abstract
Myocarditis secondary to H1N1 influenza has been described in children, but only very rarely in adults. We describe a 36-year-old man with no significant medical history who presented with flu-like symptoms of 3-week duration. When he sought medical attention, he was already manifesting heart failure secondary to fulminant myocarditis, along with multiorgan failure. Despite aggressive management, including circulatory support with a catheter-based mechanical cardiac assist device (Impella 2.5 Cardiac Assist Device, Abiomed, Danvers, MA) as a bridge to cardiac transplant, and aggressive antiviral and antibacterial therapy, the patient died of cardiac arrest. An H1N1 polymerase chain reaction postmortem assay produced positive results, and a diagnosis of fulminant viral myocarditis and multiorgan system failure was established.
Copyright ? 2011 Elsevier Inc. All rights reserved.
PMID: 21411147 [PubMed - as supplied by publisher]
Fulminant myocarditis associated with novel H1N1 influenza A.
Khouzam RN, Parizianu C, Hafiz AM, Chawla S, Schwartz R.
Division of Cardiology, Winthrop University Hospital, Mineola, New York.
Abstract
Myocarditis secondary to H1N1 influenza has been described in children, but only very rarely in adults. We describe a 36-year-old man with no significant medical history who presented with flu-like symptoms of 3-week duration. When he sought medical attention, he was already manifesting heart failure secondary to fulminant myocarditis, along with multiorgan failure. Despite aggressive management, including circulatory support with a catheter-based mechanical cardiac assist device (Impella 2.5 Cardiac Assist Device, Abiomed, Danvers, MA) as a bridge to cardiac transplant, and aggressive antiviral and antibacterial therapy, the patient died of cardiac arrest. An H1N1 polymerase chain reaction postmortem assay produced positive results, and a diagnosis of fulminant viral myocarditis and multiorgan system failure was established.
Copyright ? 2011 Elsevier Inc. All rights reserved.
PMID: 21411147 [PubMed - as supplied by publisher]