Tweet
Lancet Microbe
. 2024 Mar 14:S2666-5247(24)00037-5.
doi: 10.1016/S2666-5247(24)00037-5. Online ahead of print. Global emergence of neuraminidase inhibitor-resistant influenza A(H1N1)pdm09 viruses with I223V and S247N mutations: implications for antiviral resistance monitoring
Rhoda Cheuk-Ying Leung 1 , Jonathan Daniel Ip 2 , Lin-Lei Chen 1 , Wan-Mui Chan 2 , Kelvin Kai-Wang To 3
Affiliations
No abstract available
PubMed Disclaimer
Conflict of interest statement
We declare no competing interests. RCYL and JDI contributed equally. Data are available upon reasonable request from the corresponding author. We acknowledge the authors from originating and submitting laboratories of the influenza virus genetic sequences, which were made available through GISAID and served as the foundation of this research (Supplementary Table S4). We also acknowledge Allen Chu and Brian Chan for their technical support. This work was funded by the Partnership Programme on Enhancing Laboratory Surveillance and Investigation of Emerging Infectious Diseases and Antimicrobial Resistance for Department of Health, HKSAR; and the National Key R&D Program of China (projects 2021YFC0866100 and 2023YFC3041600). We acknowledge funding received from private donors including Richard Yu and Carol Yu, Shaw Foundation Hong Kong, Michael Seak-Kan Tong, May Tam Mak Mei Yin, Lee Wan Keung Charity Foundation, Hong Kong Sanatorium & Hospital, Respiratory Viral Research Foundation Limited, Providence Foundation Limited (in memory of the late Lui Hac-Minh), Hui Ming, Hui Hoy and Chow Sin Lan Charity Fund, Chan Yin Chuen Memorial Charitable Foundation, Marina Man-Wai Lee, the Jessie & George Ho Charitable Foundation, Kai Chong Tong, Tse Kam Ming Laurence, Foo Oi Foundation, Betty Hing-Chu Lee, and Ping Cham So. The funders had no role in study design, data collection, data analysis, data interpretation, or writing of the report. The study has been approved by the Institutional Review Board of the University of Hong Kong, Hospital Authority, Hong Kong West Cluster (UW 13–372). Written informed consent was waived because specimens were analysed in an anonymous manner. KKWT conceptualised the study. RCYL, JDI, and KKWT established the study design. RCYL, JDI, LLC, WMC, and KKWT performed data collection, data analysis, and data interpretation. RCYL, JDI, and KKWT wrote the original draft and reviewed and edited the manuscript. The corresponding author had full access to all data in the study and had final responsibility for the decision to submit for publication. Editorial note: The Lancet Group takes a neutral position with respect to territorial claims in institutional affiliations.
. 2024 Mar 14:S2666-5247(24)00037-5.
doi: 10.1016/S2666-5247(24)00037-5. Online ahead of print. Global emergence of neuraminidase inhibitor-resistant influenza A(H1N1)pdm09 viruses with I223V and S247N mutations: implications for antiviral resistance monitoring
Rhoda Cheuk-Ying Leung 1 , Jonathan Daniel Ip 2 , Lin-Lei Chen 1 , Wan-Mui Chan 2 , Kelvin Kai-Wang To 3
Affiliations
- PMID: 38493791
- DOI: 10.1016/S2666-5247(24)00037-5
No abstract available
PubMed Disclaimer
Conflict of interest statement
We declare no competing interests. RCYL and JDI contributed equally. Data are available upon reasonable request from the corresponding author. We acknowledge the authors from originating and submitting laboratories of the influenza virus genetic sequences, which were made available through GISAID and served as the foundation of this research (Supplementary Table S4). We also acknowledge Allen Chu and Brian Chan for their technical support. This work was funded by the Partnership Programme on Enhancing Laboratory Surveillance and Investigation of Emerging Infectious Diseases and Antimicrobial Resistance for Department of Health, HKSAR; and the National Key R&D Program of China (projects 2021YFC0866100 and 2023YFC3041600). We acknowledge funding received from private donors including Richard Yu and Carol Yu, Shaw Foundation Hong Kong, Michael Seak-Kan Tong, May Tam Mak Mei Yin, Lee Wan Keung Charity Foundation, Hong Kong Sanatorium & Hospital, Respiratory Viral Research Foundation Limited, Providence Foundation Limited (in memory of the late Lui Hac-Minh), Hui Ming, Hui Hoy and Chow Sin Lan Charity Fund, Chan Yin Chuen Memorial Charitable Foundation, Marina Man-Wai Lee, the Jessie & George Ho Charitable Foundation, Kai Chong Tong, Tse Kam Ming Laurence, Foo Oi Foundation, Betty Hing-Chu Lee, and Ping Cham So. The funders had no role in study design, data collection, data analysis, data interpretation, or writing of the report. The study has been approved by the Institutional Review Board of the University of Hong Kong, Hospital Authority, Hong Kong West Cluster (UW 13–372). Written informed consent was waived because specimens were analysed in an anonymous manner. KKWT conceptualised the study. RCYL, JDI, and KKWT established the study design. RCYL, JDI, LLC, WMC, and KKWT performed data collection, data analysis, and data interpretation. RCYL, JDI, and KKWT wrote the original draft and reviewed and edited the manuscript. The corresponding author had full access to all data in the study and had final responsibility for the decision to submit for publication. Editorial note: The Lancet Group takes a neutral position with respect to territorial claims in institutional affiliations.