Manufacturer Says - New second generation Anti Viral phase III study sucessful - laninamivir

[gsgs]

Re: Manufacturer Says - New second generation Anti Viral phase III study sucessful - laninamivir

OK.
"puff" is inhalation with the Relenza-diskhaler
(I read they have a newer device now)
as with Relenza ?


what will it cost ? (approximately)

[dr kockosh]

Re: Manufacturer Says - New second generation Anti Viral phase III study sucessful - laninamivir

hard to tell what price will be but manafacture should be cheaper for 1 dose as apposed to ten and stockpiling/transport so i guess about the same as existing antivirals - so biota will get a big fat profit - i believe they have a new portugeuse inhaler which is high tech compared with relenza

[dr kockosh]

Re: Manufacturer Says - New second generation Anti Viral phase III study sucessful - laninamivir

biota talking with a hand full of drug co including GSK and Roche on licensing agreement for LANI.
CEO peter Cook tells reuters interview emergency pandemic enactment could see lani in use within 12 mths

[dr kockosh]

Re: Manufacturer Says - New second generation Anti Viral phase III study sucessful - laninamivir

Experimental drug helps save critical swine flu victim<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" /><o:p></o:p>

GRANT McARTHUR<o:p></o:p>
August 19, 2009 12:01am<o:p></o:p>
GIVEN virtually no hope of survival, Ivan Luong has stunned doctors after recovering from swine flu with the help of a world-first experimental drug.<o:p></o:p>
As the 20-year-old left intensive care last night following a marathon 38 days ? including 31 on breathing machines ? a team from Melbourne's The Austin hospital were still coming to terms with how they had saved the chronic asthmatic.<o:p></o:p>
After arriving at the hospital on July 10, Mr Luong's lungs became so full of mucus they were almost solid, going from about 200g to more than 1kg and having no chance of passing oxygen into his blood.<o:p></o:p>
Efforts to sustain him on traditional ventilators literally blew Mr Luong's lungs apart - causing air to fill his chest cavity and place pressure on his heart as well as dangerous pockets of air under his skin.<o:p></o:p>
As his condition worsened an examination of the student's stomach revealed it had shut down, meaning the Tamiflu needed to fight off swine flu could not be digested.<o:p></o:p>
With an intravenous drip the only way of getting medication into Mr Luong, the team decided to try a liquid form of flu drug Relenza ? a highly experimental formula not registered anywhere in the world, which had to be flown in from the U.S. where it had been produced for clinical trials unrelated to swine flu.<o:p></o:p>
A relieved Mr Luong was yesterday coming to terms with enormous effort made to save his life. "All I can remember is getting needles about 40 days ago," he said.<o:p></o:p>
"I have strong parents that love me and have prayed for me." <o:p></o:p>
In Adelaide yesterday, a Hove man, 37, suffering from swine flu with no underlying medical conditions died, becoming the 11th death in South Australia.<o:p></o:p>
<o:p></o:p>
here's an example of an existing drug being used in a new way - exactly what we need with tamiflu resistance on the rise.
This also heighlights the potential for reduced absorbtion in patients who are administered oral anti virals (tamiflu)while going into shock or having vomiting symptoms.The question is - how much of the tamiflu is being absorbed.