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Pediatr Transplant. 2011 Mar 23. doi: 10.1111/j.1399-3046.2011.01490.x. [Epub ahead of print]
A severely immunocompromised child with uncomplicated oseltamivir-resistant 2009 H1N1 pandemic influenza infection.
Hyle EP, Shu B, Lindstrom S, Klimov A, Hancock K, Ferraro MJ, Traum AZ, Michelow IC.
Department of Medicine, Massachusetts General Hospital, Boston, MA, USA Center for Disease Control, Atlanta, GA, USA Department of Pathology Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA.
Abstract
Hyle EP, Shu B, Lindstrom S, Klimov A, Hancock K, Ferraro MJ, Traum AZ, Michelow IC. A severely immunocompromised child with uncomplicated oseltamivir-resistant 2009 H1N1 pandemic influenza infection. Pediatr Transplantation 2011. ? 2011 John Wiley & Sons A/S. Abstract: 2009 H1N1 pandemic influenza was associated with increased risk for severe disease in children and the immunosuppressed. We report a case of uncomplicated pneumonia because of infection with oseltamivir-resistant 2009 H1N1 virus in an immunosuppressed pediatric renal transplant patient. Innate immunity and/or altered viral fitness may be responsible for the mild clinical phenotype of the case.
? 2011 John Wiley & Sons A/S.
PMID: 21429059 [PubMed - as supplied by publisher]
A severely immunocompromised child with uncomplicated oseltamivir-resistant 2009 H1N1 pandemic influenza infection.
Hyle EP, Shu B, Lindstrom S, Klimov A, Hancock K, Ferraro MJ, Traum AZ, Michelow IC.
Department of Medicine, Massachusetts General Hospital, Boston, MA, USA Center for Disease Control, Atlanta, GA, USA Department of Pathology Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA.
Abstract
Hyle EP, Shu B, Lindstrom S, Klimov A, Hancock K, Ferraro MJ, Traum AZ, Michelow IC. A severely immunocompromised child with uncomplicated oseltamivir-resistant 2009 H1N1 pandemic influenza infection. Pediatr Transplantation 2011. ? 2011 John Wiley & Sons A/S. Abstract: 2009 H1N1 pandemic influenza was associated with increased risk for severe disease in children and the immunosuppressed. We report a case of uncomplicated pneumonia because of infection with oseltamivir-resistant 2009 H1N1 virus in an immunosuppressed pediatric renal transplant patient. Innate immunity and/or altered viral fitness may be responsible for the mild clinical phenotype of the case.
? 2011 John Wiley & Sons A/S.
PMID: 21429059 [PubMed - as supplied by publisher]
