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Published: 2 February 2025
https://doi.org/10.3390/vetsci12020113 (registering DOI)
Loureiro, F.; Mesquita, J.R.; Cardoso, L.; Matos, A.C.; Matos, M.; Coelho, A.C.
Simple Summary
The flaviviruses (family Flaviviridae) comprise aetiological agents of neurological diseases in animals and humans, which are spread worldwide. The Bagaza virus (BAGV), a member of the genus Orthoflavivirus, is a mosquito-borne arbovirus with wild birds as amplifying hosts. BAGV is still not well-documented in human health but has already been identified several times in bird species on the European continent. BAGV has been introduced into Spain in at least three independent outbreaks and has also been detected in Portugal and France. In this scoping review, 114 studies were initially evaluated and 12 were included after applying the exclusion criteria.
Abstract
The Bagaza virus (BAGV) belongs to the genus Orthoflavivirus (Ntaya serocomplex) and emerged in Europe, Spain, in 2010. The natural transmission cycle of this virus is perpetuated by Culex spp. mosquitoes and viraemic birds. The ability of BAGV to cause infection in several game birds from the family Phasianidae has been well-studied. BAGV is antigenically similar to other orthoflaviviruses from the Japanese encephalitis serocomplex, such as the West Nile and Usutu viruses, a circumstance which can lead to cross-reactivity in less specific serological techniques (e.g., ELISA). Severe implications in animal health has already been described, but some aspects of the dynamics of transmission and the limits of zoonotic potential of BAGV still need to be clarified. Further investigation focused on epidemiological surveillance in high-risk areas would be beneficial for prevention and control of new outbreaks. The present study is a systematic review of the BAGV reports in Europe.
https://doi.org/10.3390/vetsci12020113 (registering DOI)
Loureiro, F.; Mesquita, J.R.; Cardoso, L.; Matos, A.C.; Matos, M.; Coelho, A.C.
Simple Summary
The flaviviruses (family Flaviviridae) comprise aetiological agents of neurological diseases in animals and humans, which are spread worldwide. The Bagaza virus (BAGV), a member of the genus Orthoflavivirus, is a mosquito-borne arbovirus with wild birds as amplifying hosts. BAGV is still not well-documented in human health but has already been identified several times in bird species on the European continent. BAGV has been introduced into Spain in at least three independent outbreaks and has also been detected in Portugal and France. In this scoping review, 114 studies were initially evaluated and 12 were included after applying the exclusion criteria.
Abstract
The Bagaza virus (BAGV) belongs to the genus Orthoflavivirus (Ntaya serocomplex) and emerged in Europe, Spain, in 2010. The natural transmission cycle of this virus is perpetuated by Culex spp. mosquitoes and viraemic birds. The ability of BAGV to cause infection in several game birds from the family Phasianidae has been well-studied. BAGV is antigenically similar to other orthoflaviviruses from the Japanese encephalitis serocomplex, such as the West Nile and Usutu viruses, a circumstance which can lead to cross-reactivity in less specific serological techniques (e.g., ELISA). Severe implications in animal health has already been described, but some aspects of the dynamics of transmission and the limits of zoonotic potential of BAGV still need to be clarified. Further investigation focused on epidemiological surveillance in high-risk areas would be beneficial for prevention and control of new outbreaks. The present study is a systematic review of the BAGV reports in Europe.
