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(Reuters) - People who got immunized against the 1976 "swine flu" epidemic that never happened may have benefited from the shots after all -- they may have been protected from the 2009 H1N1 swine flu strain.
Health
Tests of blood from medical staff and their spouses showed those who had been vaccinated in 1976 had evidence of extra immune protection against both the 2009 H1N1 swine flu and the seasonal strain of H1N1 that circulated the year before.
"We gave this vaccine to 45 million people and it was declared one of the greatest public health blunders of all time, and now we are finding out that it actually did some good," said Dr. Jonathan McCullers of St. Jude Children's Research Hospital in Memphis, Tennessee, who led the study published in the journal Clinical Infectious Diseases.
The study, published on Friday, supports a theory that different strains of flu virus cycle in and out of circulation and that getting a flu vaccine every year may protect people from as-yet unseen flu strains in the future.
"Our research shows that while immunity among those vaccinated in 1976 has waned somewhat, they mounted a much stronger immune response against the current pandemic H1N1 strain than others who did not receive the 1976 vaccine," McCullers said.
Every year, several different strains of influenza circulate. The viruses are mutation-prone and change a little bit every year, forcing vaccine-makers to reformulate the seasonal flu vaccine cocktail every year too.
"You never know with flu -- more immunity is always good," McCullers said in a telephone interview.
Several times a century, a new strain pops up and causes a pandemic. That happened in 1918 with H1N1, 1957 with H2N2 and 1968 with H3N2. Usually, the new pandemic strain settles down and joins the seasonal mix, which may eventually happen with the 2009 H1N1 strain.
In 1976, a new strain of H1N1 broke out at an Army base in New Jersey and U.S. officials, worried about a pandemic, rushed out a vaccine and pushed hard to vaccinate the population.
The virus never spread off the base and the vaccine was linked with a rare but devastating side effect called Guillain Barre syndrome. Many Americans have been suspicious of vaccines ever since.
Health
Tests of blood from medical staff and their spouses showed those who had been vaccinated in 1976 had evidence of extra immune protection against both the 2009 H1N1 swine flu and the seasonal strain of H1N1 that circulated the year before.
"We gave this vaccine to 45 million people and it was declared one of the greatest public health blunders of all time, and now we are finding out that it actually did some good," said Dr. Jonathan McCullers of St. Jude Children's Research Hospital in Memphis, Tennessee, who led the study published in the journal Clinical Infectious Diseases.
The study, published on Friday, supports a theory that different strains of flu virus cycle in and out of circulation and that getting a flu vaccine every year may protect people from as-yet unseen flu strains in the future.
"Our research shows that while immunity among those vaccinated in 1976 has waned somewhat, they mounted a much stronger immune response against the current pandemic H1N1 strain than others who did not receive the 1976 vaccine," McCullers said.
Every year, several different strains of influenza circulate. The viruses are mutation-prone and change a little bit every year, forcing vaccine-makers to reformulate the seasonal flu vaccine cocktail every year too.
"You never know with flu -- more immunity is always good," McCullers said in a telephone interview.
Several times a century, a new strain pops up and causes a pandemic. That happened in 1918 with H1N1, 1957 with H2N2 and 1968 with H3N2. Usually, the new pandemic strain settles down and joins the seasonal mix, which may eventually happen with the 2009 H1N1 strain.
In 1976, a new strain of H1N1 broke out at an Army base in New Jersey and U.S. officials, worried about a pandemic, rushed out a vaccine and pushed hard to vaccinate the population.
The virus never spread off the base and the vaccine was linked with a rare but devastating side effect called Guillain Barre syndrome. Many Americans have been suspicious of vaccines ever since.
