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High Dose Intravenous Vitamin C Treatment for Zika Fever

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  • High Dose Intravenous Vitamin C Treatment for Zika Fever

    High Dose Intravenous Vitamin C Treatment for Zika Fever
    Michael J. Gonzalez, NMD, DSc, PhD, FACN;1 Miguel J. Berdie,l MD;2 Jorg? R. Miranda-
    Massari, PharmD;2 Jorg? Duconge, PhD;1 Joshua L. Rodr?guez-L?pez, BS;3 Pedro A.
    Adrover-L?pez, BS 3
    ?University of Puerto Rico, Medical Sciences Campus, Schools of Public Health and Pharmacy, San Juan, PR, 00936-5067
    ?Berdiel Clinic, Ponce, PR, 00716
    3Ponce Health Sciences University, School of Medicine, Ponce, PR, 00716


    Zika Fever is a viral disease caused by a single-stranded RNA virus from the Flavivirus
    genus, Flaviviridae family, from the Spondweni group. Its transmission occurs through
    mosquito vectors, principally Aedes Aegypti. !e most common symptoms of Zika are fever, rash, joint
    pain, and conjunctivitis (red eyes). Other common symptoms include muscle pain and headache. As of
    now, no vaccine exists for the virus and no official treatment has been developed aside from standard
    procedures of the use of acetaminophen (paracetamol) and non-steroidal anti-infammatory drugs.
    !is is a case report of a 54 year-old Hispanic female who arrived at the clinic with symptomatology
    congruent with the Zika fever. !e patient was treated with high doses of intravenous vitamin C
    over three days. !e symptoms resolved after the infusions without any side effects at day four. Recovery
    from this viral infection takes normally around two weeks. Based on the positive outcome in
    this case, we propose that intravenous vitamin C should be studied further as a potential treatment
    for acute viral infections.

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