Mexico - Outbreaks of highly pathogenic avian influenza H7N3 in backyard birds and farms

[Pathfinder]

Highly pathogenic avian influenza, Mexico

Information received on 02/04/2019 from MVZ Joaquín Braulio Delgadillo Álvarez, Director General de Salud Animal, Servicio Nacional de Sanidad, Inocuidad y Calidad Agroalimentaria (SENASICA) Secretaría de Agricultura, Ganadería, Desarrollo Rural, Pesca y Alimentación, Ministerio de Agricultura, Ganadería, Desarrollo Rural, Pesca y Alimentación, México, Mexico

Summary Report type Immediate notification Date of start of the event 06/03/2019 Date of confirmation of the event 10/03/2019 Report date 01/04/2019 Date submitted to OIE 02/04/2019 Reason for notification Recurrence of a listed disease Date of previous occurrence 18/04/2018 Manifestation of disease Clinical disease Causal agent Virus de la influenza aviar altamente patógeno Serotype H7N3 Nature of diagnosis Laboratory (advanced) This event pertains to a defined zone within the country

New outbreaks (1)

Outbreak 1 Acolman, Mexico Date of start of the outbreak 06/03/2019 Outbreak status Resolved (22/03/2019) Epidemiological unit Backyard Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 150 150 150 0 0 Affected population Se trata de un predio de traspatio con 150 aves criollas, detectado por una notificación por alta mortalidad y con signos clínicos sugerentes a la enfermedad (cianosis, edema y tumefacción en cresta y barbillas y muerte súbita).

Summary of outbreaks Total outbreaks: 1 Total animals affected Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 150 150 150 0 0 Outbreak statistics Species Apparent morbidity rate Apparent mortality rate Apparent case fatality rate Proportion susceptible animals lost* Birds 100.00% 100.00% 100.00% 100.00% *Removed from the susceptible population through death, destruction and/or slaughter

Epidemiology Source of the outbreak(s) or origin of infection Unknown or inconclusive Epidemiological comments Los cadáveres de las aves fueron dispuestos sanitariamente dentro del predio afectado, así mismo se realizaron acciones de limpieza, lavado y desinfección de las instalaciones. Se mantiene la vigilancia de los predios localizados en el área perifocal sin que hasta el momento haya evidencia de aves enfermas o muertas. Cabe señalar que el estado de México tiene una condición sanitaria como de escasa prevalencia en la que se aplica la vacuna contra el virus de la influenza aviar H7N3, previa autorización del SENASICA.

Control measures Measures applied Movement control inside the country Surveillance outside containment and/or protection zone Surveillance within containment and/or protection zone Official destruction of animal products Official disposal of carcasses, by-products and waste Stamping out Vaccination permitted (if a vaccine exists) No treatment of affected animals Measures to be applied No other measures

Diagnostic test results Laboratory name and type Species Test Test date Result Laboratorio de bioseguridad nivel 3 del SENASICA (National laboratory) Birds intravenous pathogenicity index (IVPI) test 10/03/2019 Positive Laboratorio de bioseguridad nivel 3 del SENASICA (National laboratory) Birds virus isolation 08/03/2019 Positive Laboratorio de bioseguridad nivel 3 del SENASICA (National laboratory) Birds virus sequencing 22/03/2019 Positive

Future Reporting The event is continuing. Weekly follow-up reports will be submitted.

...
http://www.oie.int/wahis_2/public/wa...reportid=30012

[Pathfinder]

Highly pathogenic avian influenza, Mexico

Information received on 17/04/2019 from Dr. Juan Gay Gutiérrez, Director General de Salud Animal, Servicio Nacional de Sanidad, Inocuidad y Calidad Agroalimentaria (SENASICA), Secretaría de Agricultura y Desarrollo, Mexico DF, Mexico

Summary Report type Follow-up report No. 1 Date of start of the event 06/03/2019 Date of confirmation of the event 10/03/2019 Report date 16/04/2019 Date submitted to OIE 17/04/2019 Reason for notification Recurrence of a listed disease Date of previous occurrence 18/04/2018 Manifestation of disease Clinical disease Causal agent Highly pathogenic avian influenza virus Serotype H7N3 Nature of diagnosis Clinical, Laboratory (advanced) This event pertains to a defined zone within the country Related reports Immediate notification (01/04/2019) Follow-up report No. 1 (16/04/2019)

New outbreaks (3)

Outbreak 1 Lagos de Moreno, Jalisco Date of start of the outbreak 09/04/2019 Outbreak status Resolved (14/04/2019) Epidemiological unit Backyard Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 1625 1625 400 1225 0 Affected population Reporting of a high mortality in a backyard with fighting cocks. Quarantine was imposed immediately and fallowing, cleaning and disinfection of the premises are ongoing.

Outbreak 2 Lagos de Moreno, Jalisco Date of start of the outbreak 09/04/2019 Outbreak status Resolved (14/04/2019) Epidemiological unit Backyard Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 612 612 120 492 0 Affected population Reporting of a high mortality in a backyard with birds. Quarantine was imposed and fallowing, cleaning and disinfection of the premises were carried out immediately.

Outbreak 3 Chapa de Mota, Mexico Date of start of the outbreak 09/04/2019 Outbreak status Resolved (16/04/2019) Epidemiological unit Backyard Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 290 290 230 60 0 Affected population Reporting of a high mortality in a backyard with birds. At the time of the visit, there were only 60 sick animals left, the remaining animals had then already died. Quarantine was imposed and fallowing, cleaning and disinfection of the premises were carried out immediately.

Summary of outbreaks Total outbreaks: 3 Total animals affected Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 2527 2527 750 1777 0 Outbreak statistics Species Apparent morbidity rate Apparent mortality rate Apparent case fatality rate Proportion susceptible animals lost* Birds 100.00% 29.68% 29.68% 100.00% *Removed from the susceptible population through death, destruction and/or slaughter

Epidemiology Source of the outbreak(s) or origin of infection Unknown or inconclusive Epidemiological comments The States where the outbreaks were located correspond to the region of low prevalence in which vaccination against the H7N3 avian influenza virus is applicable subject to prior authorisation by SENASICA.

Control measures Measures applied Movement control inside the country Surveillance outside containment and/or protection zone Surveillance within containment and/or protection zone Quarantine Official disposal of carcasses, by-products and waste Stamping out Vaccination prohibited No treatment of affected animals Measures to be applied No other measures

Future Reporting The event is continuing. Weekly follow-up reports will be submitted.

...
http://www.oie.int/wahis_2/public/wa...reportid=30189

[Pathfinder]

Highly pathogenic avian influenza, Mexico

Information received on 27/04/2019 from Dr. Juan Gay Gutiérrez, Director General de Salud Animal, Servicio Nacional de Sanidad, Inocuidad y Calidad Agroalimentaria (SENASICA), Secretaría de Agricultura y Desarrollo, Mexico DF, Mexico

Summary Report type Follow-up report No. 2 Date of start of the event 06/03/2019 Date of confirmation of the event 10/03/2019 Report date 26/04/2019 Date submitted to OIE 27/04/2019 Reason for notification Recurrence of a listed disease Date of previous occurrence 18/04/2018 Manifestation of disease Clinical disease Causal agent Virus de la influenza aviar altamente patógena Serotype H7N3 Nature of diagnosis Clinical, Laboratory (advanced) This event pertains to a defined zone within the country Related reports Immediate notification (01/04/2019) Follow-up report No. 1 (16/04/2019) Follow-up report No. 2 (26/04/2019)

New outbreaks (2)

Outbreak 1 Colon, Queretaro Date of start of the outbreak 08/04/2019 Outbreak status Resolved (19/04/2019) Epidemiological unit Farm Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 138632 5 0 138632 0 Affected population The presence of highly pathogenic avian influenza was detected as part of active epidemiological surveillance in a poultry production unit in five birds that were subjected to organ sampling and did not show any clinical signs, as the rest of the flock.

Outbreak 2 Mineral del Chico, Hidalgo Date of start of the outbreak 15/04/2019 Outbreak status Continuing (or date resolved not provided) Epidemiological unit Backyard Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 598 178 172 0 0 Affected population A rural production unit with 598 birds, detected and reported to the competent authority by a self-employed veterinarian in order to carry out appropriate epidemiological monitoring.

Summary of outbreaks Total outbreaks: 2 Total animals affected Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 139230 183 172 138632 0 Outbreak statistics Species Apparent morbidity rate Apparent mortality rate Apparent case fatality rate Proportion susceptible animals lost* Birds 0.13% 0.12% 93.99% 99.69% *Removed from the susceptible population through death, destruction and/or slaughter

Epidemiology Source of the outbreak(s) or origin of infection Unknown or inconclusive Epidemiological comments Active epidemiological surveillance has been established in Mexico as well as a (passive) notification system. These two strategies have identified two outbreaks, located in the region of low prevalence in which vaccination against the H7N3 avian influenza virus is applicable subject to prior authorisation by SENASICA.

Control measures Measures applied Movement control inside the country Surveillance outside containment and/or protection zone Surveillance within containment and/or protection zone Quarantine Vaccination permitted (if a vaccine exists) No treatment of affected animals Measures to be applied Official disposal of carcasses, by-products and waste Stamping out Disinfection Ante and post-mortem inspections

Future Reporting The event is continuing. Weekly follow-up reports will be submitted.

...
http://www.oie.int/wahis_2/public/wa...reportid=30322

[Pathfinder]

Highly pathogenic avian influenza, Mexico

Information received on 18/05/2019 from Dr. Juan Gay Gutiérrez, Director General de Salud Animal, Servicio Nacional de Sanidad, Inocuidad y Calidad Agroalimentaria (SENASICA), Secretaría de Agricultura y Desarrollo Rural (SADER), Ciudad de Mexico, Mexico

Summary Report type Follow-up report No. 3 Date of start of the event 06/03/2019 Date of confirmation of the event 10/03/2019 Report date 17/05/2019 Date submitted to OIE 18/05/2019 Reason for notification Recurrence of a listed disease Date of previous occurrence 18/04/2018 Manifestation of disease Clinical disease Causal agent Highly pathogenic avian influenza virus Serotype H7N3 Nature of diagnosis Clinical, Laboratory (advanced) This event pertains to a defined zone within the country Related reports Immediate notification (01/04/2019) Follow-up report No. 1 (16/04/2019) Follow-up report No. 2 (26/04/2019) Follow-up report No. 3 (17/05/2019)

New outbreaks (5)

Outbreak 1 Colón, Queretaro Date of start of the outbreak 24/04/2019 Outbreak status Resolved (02/05/2019) Epidemiological unit Backyard Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 1 1 0 1 0 Affected population As a result of the epidemiological surveillance, samples were taken in a backyard with one bird with no clinical signs; the virus was isolated.

Outbreak 2 Ezequiel Montes, Queretaro Date of start of the outbreak 29/04/2019 Outbreak status Resolved (07/05/2019) Epidemiological unit Backyard Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 62 50 42 20 0 Affected population As a result of the epidemiological surveillance, the disease was detected in a backyard with 62 birds. High mortality was observed in the premises; samples were therefore taken for virus isolation.

Outbreak 3 General Heliodoro Castillo, Guerrero Date of start of the outbreak 30/04/2019 Outbreak status Resolved (08/05/2019) Epidemiological unit Backyard Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 34 24 19 15 0 Affected population Backyard with 34 birds detected following high mortality and clinical signs suggesting highly pathogenic avian influenza (cyanosis, edema and swelling on red comb and wattles and sudden death).

Outbreak 4 Tlaxco, Tlaxcala Date of start of the outbreak 30/04/2019 Outbreak status Resolved (07/05/2019) Epidemiological unit Backyard Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 10 5 5 5 0 Affected population Backyard with 10 birds detected following high mortality and clinical signs suggesting highly pathogenic avian influenza (cyanosis, edema and swelling on red comb and wattles and sudden death).

Outbreak 5 Pedro Escobedo, Queretaro Date of start of the outbreak 07/05/2019 Outbreak status Continuing (or date resolved not provided) Epidemiological unit Farm Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 2000 1400 1200 0 0 Affected population Commercial laying farm with 2,000 birds detected following high mortality and clinical signs suggesting highly pathogenic avian influenza (cyanosis, edema and swelling on red comb and wattles and sudden death).

Summary of outbreaks Total outbreaks: 5 Total animals affected Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 2107 1480 1266 41 0 Outbreak statistics Species Apparent morbidity rate Apparent mortality rate Apparent case fatality rate Proportion susceptible animals lost* Birds 70.24% 60.09% 85.54% 62.03% *Removed from the susceptible population through death, destruction and/or slaughter

Epidemiology Source of the outbreak(s) or origin of infection Unknown or inconclusive Epidemiological comments As a result of actions implemented to reinforce epidemiological surveillance in the State of Querétaro, two outbreaks of highly pathogenic avian influenza were identified, both backyard premises without clinical signs. Two other outbreaks were reported in backyard premises in the States of Tlaxcala and Guerrero and one outbreak in a commercial laying farm in the State of Querétaro. Surveillance is maintained in the zone around the affected farms without any evidence so far of sick or dead birds. The States of Querétaro, Tlaxcala and Guerrero have a low prevalence and vaccination against avian influenza virus H7N3 is applied, prior authorization from SENASICA. In the reported outbreaks of Mineral del Chico, Hidalgo; Colón, Querétaro (two outbreaks); Ezequiel Montes, Querétaro; Tlaxco, Tlaxcala and General Heliodoro Castillo, Guerrero, all the birds were killed and the carcasses, by-products and waste were officially disposed of, and the facilities were cleaned and disinfected. Likewise, IVPI results were obtained: 2.13, 2.53, 2.41, 2.43, 2.49 and 2.58, respectively.

Control measures Measures applied Movement control inside the country Surveillance outside containment and/or protection zone Surveillance within containment and/or protection zone Quarantine Slaughter Vaccination permitted (if a vaccine exists) No treatment of affected animals Measures to be applied Official disposal of carcasses, by-products and waste Stamping out Disinfection Ante and post-mortem inspections

Future Reporting The event is continuing. Weekly follow-up reports will be submitted.

...
http://www.oie.int/wahis_2/public/wa...reportid=30510

[Pathfinder]

Highly pathogenic avian influenza, Mexico

Information received on 06/06/2019 from Dr. Juan Gay Gutiérrez, Director General de Salud Animal, Servicio Nacional de Sanidad, Inocuidad y Calidad Agroalimentaria (SENASICA), Secretaría de Agricultura y Desarrollo Rural (SADER), Ciudad de Mexico, Mexico

Summary Report type Follow-up report No. 4 Date of start of the event 06/03/2019 Date of confirmation of the event 10/03/2019 Report date 04/06/2019 Date submitted to OIE 06/06/2019 Reason for notification Recurrence of a listed disease Date of previous occurrence 18/04/2018 Manifestation of disease Clinical disease Causal agent Highly pathogenic avian influenza virus Serotype H7N3 Nature of diagnosis Clinical, Laboratory (advanced) This event pertains to a defined zone within the country Related reports Immediate notification (01/04/2019) Follow-up report No. 1 (16/04/2019) Follow-up report No. 2 (26/04/2019) Follow-up report No. 3 (17/05/2019) Follow-up report No. 4 (04/06/2019)

New outbreaks (4)

Outbreak 1 General Heliodoro Castillo, Guerrero Date of start of the outbreak 08/05/2019 Outbreak status Continuing (or date resolved not provided) Epidemiological unit Backyard Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 54 14 10 0 0 Affected population As a result of sampling around the outbreaks, the disease was detected in a backyard with 54 birds. High mortality was observed in the premises; samples were therefore taken for virus isolation.

Outbreak 2 Cadereyta de Montes, Queretaro Date of start of the outbreak 14/05/2019 Outbreak status Resolved (01/06/2019) Epidemiological unit Backyard Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 25 5 0 25 0 Affected population As a result of the epidemiological surveillance, tracheal swabs were taken in five birds in a backyard with 25 birds; no clinical signs observed.

Outbreak 3 Tizayuca, Hidalgo Date of start of the outbreak 14/05/2019 Outbreak status Resolved (30/05/2019) Epidemiological unit Farm Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 1300 1200 1150 150 0 Affected population Commercial laying farm with 1,300 birds detected following high mortality and clinical signs suggesting highly pathogenic avian influenza (cyanosis, edema and swelling on red comb and wattles and sudden death).

Outbreak 4 San Juan del Río, Queretaro Date of start of the outbreak 20/05/2019 Outbreak status Resolved (31/05/2019) Epidemiological unit Farm Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 133566 5 0 133566 0 Affected population As a result of the epidemiological surveillance, tracheal swabs were taken in five birds in a commercial laying farm with 133,566 birds; no clinical signs observed.

Summary of outbreaks Total outbreaks: 4 Total animals affected Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 134945 1224 1160 133741 0 Outbreak statistics Species Apparent morbidity rate Apparent mortality rate Apparent case fatality rate Proportion susceptible animals lost* Birds 0.91% 0.86% 94.77% 99.97% *Removed from the susceptible population through death, destruction and/or slaughter

Epidemiology Source of the outbreak(s) or origin of infection Unknown or inconclusive Epidemiological comments Virus isolation was carried out in both backyards and in both commercial laying farms and the following IVPI results were obtained: 2.55 (General Heliodoro Castillo), 2.69 (Cadereyta de Montes) and 2.52 (Tizayuca). Quarantines were established as well as bans on movements in and out. All the birds were killed and the carcasses, by-products and waste were officially disposed of, and the facilities were cleaned and disinfected, except for the backyard in General Heliodoro Castillo, where measures are still on-going. The States of Querétaro, Hidalgo and Guerrero have a low prevalence and vaccination against avian influenza virus H7N3 is applied, prior authorization from SENASICA.

Control measures Measures applied Movement control inside the country Surveillance outside containment and/or protection zone Surveillance within containment and/or protection zone Quarantine Slaughter Vaccination permitted (if a vaccine exists) No treatment of affected animals Measures to be applied Official disposal of carcasses, by-products and waste Stamping out Disinfection Ante and post-mortem inspections

Future Reporting The event is continuing. Weekly follow-up reports will be submitted.

...
http://www.oie.int/wahis_2/public/wa...reportid=30704

[Pathfinder]

Highly pathogenic avian influenza, Mexico

Information received on 09/07/2019 from Dr. Juan Gay Gutiérrez, Director General de Salud Animal, Servicio Nacional de Sanidad, Inocuidad y Calidad Agroalimentaria (SENASICA), Secretaría de Agricultura y Desarrollo Rural (SADER), Ciudad de Mexico, Mexico

Summary Report type Follow-up report No. 6 Date of start of the event 06/03/2019 Date of confirmation of the event 10/03/2019 Report date 08/07/2019 Date submitted to OIE 09/07/2019 Reason for notification Recurrence of a listed disease Date of previous occurrence 18/04/2018 Manifestation of disease Clinical disease Causal agent Highly pathogenic avian influenza virus Serotype H7N3 Nature of diagnosis Clinical, Laboratory (advanced) This event pertains to a defined zone within the country Related reports Immediate notification (01/04/2019) Follow-up report No. 1 (16/04/2019) Follow-up report No. 2 (26/04/2019) Follow-up report No. 3 (17/05/2019) Follow-up report No. 4 (04/06/2019) Follow-up report No. 5 (19/06/2019) Follow-up report No. 6 (08/07/2019)

New outbreaks (3)

Outbreak 1 Tasquillo, Hidalgo Date of start of the outbreak 06/06/2019 Outbreak status Resolved (19/06/2019) Epidemiological unit Backyard Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 1000 1000 1000 0 0 Affected population Backyard farm with 1,000 birds detected following notification of high mortality and clinical signs suggesting highly pathogenic avian influenza (cyanosis, edema and swelling on red comb and wattles and sudden death).

Outbreak 2 Tlajomulco de Zuñiga, Jalisco Date of start of the outbreak 11/06/2019 Outbreak status Resolved (13/06/2019) Epidemiological unit Backyard Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 210 10 10 200 0 Affected population Backyard farm with 210 birds detected following notification of high mortality and clinical signs suggesting highly pathogenic avian influenza (cyanosis, edema and swelling on red comb and wattles and sudden death).

Outbreak 3 Santa Cruz de Juventino Rosas, Guanajuato Date of start of the outbreak 19/06/2019 Outbreak status Resolved (21/06/2019) Epidemiological unit Backyard Affected animals Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 50 30 25 25 0 Affected population Backyard farm with 50 birds detected following notification of high mortality and clinical signs suggesting highly pathogenic avian influenza (cyanosis, edema and swelling on red comb and wattles and sudden death).

Summary of outbreaks Total outbreaks: 3 Total animals affected Species Susceptible Cases Deaths Killed and disposed of Slaughtered Birds 1260 1040 1035 225 0 Outbreak statistics Species Apparent morbidity rate Apparent mortality rate Apparent case fatality rate Proportion susceptible animals lost* Birds 82.54% 82.14% 99.52% 100.00% *Removed from the susceptible population through death, destruction and/or slaughter

Epidemiology Source of the outbreak(s) or origin of infection Unknown or inconclusive Epidemiological comments Three backyards in the States of Hidalgo, Jalisco and Guanajuato, in which virus isolation has been carried out, have been notified. For the outbreak in Hidalgo, a result of 2.51 was obtained via an IVPI test. In all outbreaks, a ban on the entry and exit of birds was enforced, a definitive quarantine was established, all birds were slaughtered, and all carcasses, products and waste were disposed of, and the facilities were cleaned and disinfected. The States of Hidalgo, Jalisco and Guanajuato have a low prevalence of disease and the H7N3 avian influenza virus vaccine is applied, with prior authorization from SENASICA.

Control measures Measures applied Movement control inside the country Surveillance outside containment and/or protection zone Surveillance within containment and/or protection zone Quarantine Official disposal of carcasses, by-products and waste Stamping out Disinfection Slaughter Ante and post-mortem inspections Vaccination permitted (if a vaccine exists) No treatment of affected animals Measures to be applied No other measures

Future Reporting The event is continuing. Weekly follow-up reports will be submitted.

...
http://www.oie.int/wahis_2/public/wa...reportid=31010