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Highly Pathogenic Avian Influenza (HPAI) Poultry Innovation Grand Challenge Funding Opportunity
Last Modified: March 20, 2025 Application Deadline:
May 19, 2025 at 11:59 PM EST
Opportunity Number:
USDA-APHIS-10025-VSSP0000-25-0015
Opportunity Type:
Cooperative Agreement or Interagency Agreement
Catalog of Federal Domestic Assistance Number:
10.025, Plant and Animal Disease, Pest Control, and Animal Care
APHIS is announcing the availability of funding to support the new comprehensive strategy to curb highly pathogenic avian influenza (HPAI), protect the U.S. poultry industry, and lower egg prices.
Through this opportunity, APHIS is investing up to $100 million to support projects in the following priority topics:
Download Notice of Funding Opportunity and Instructions for Applicants (472.57 KB)
Download Guidelines for Use of Funds (366.71 KB)
View Frequently Asked Questions
Application Details
New to APHIS Funding?
Before you can apply, you’ll need to set up a Login.gov account, an ezFedGrants account, and be registered with the U.S. Government System for Award Management (SAM). Don't wait! It takes at least 10 business days for new SAM registrations to process.
Learn more about the basics of our funding process and how you can get ready to apply.
Use the templates and information below to develop your application package. All materials must be included, unless otherwise noted.
Application Package
Application packages must include a Work Plan and Financial Plan (see templates below). Packages must also include a completed SF-424, Application for Federal Assistance and SF-424-A, Budget Information for Non-Construction Programs; you’ll complete these forms within ezFedGrants.
Work Plan Template
Financial Plan Template
Eligible Entities
The following entities are eligible to apply for this funding opportunity:
* These entities require additional review and approval processes. For more information, contact us at sm.ap.hpai.challenge@usda.gov. Application Deadline
The application deadline is May 19, 2025, 11:59 PM EDT. Applications received after this deadline will not be considered for funding.
If you're a non-Federal applicant, you must submit all application materials via ezFedGrants. Locate this opportunity on ezFedGrants or on Grants.gov using the opportunity and catalog numbers found at the top of this page.
Apply Now: Non-Federal Applicants
If you're a Federal applicant, you must submit your application materials via email to sm.ap.hpai.challenge@usda.gov.
Last Modified: March 20, 2025 Application Deadline:
May 19, 2025 at 11:59 PM EST
Opportunity Number:
USDA-APHIS-10025-VSSP0000-25-0015
Opportunity Type:
Cooperative Agreement or Interagency Agreement
Catalog of Federal Domestic Assistance Number:
10.025, Plant and Animal Disease, Pest Control, and Animal Care
APHIS is announcing the availability of funding to support the new comprehensive strategy to curb highly pathogenic avian influenza (HPAI), protect the U.S. poultry industry, and lower egg prices.
Through this opportunity, APHIS is investing up to $100 million to support projects in the following priority topics:
- Develop novel vaccines to protect poultry from HPAI
- Develop novel therapeutics to address HPAI in poultry
- Conduct research to further understand avian influenza in poultry and to improve response strategies
Download Notice of Funding Opportunity and Instructions for Applicants (472.57 KB)
Download Guidelines for Use of Funds (366.71 KB)
View Frequently Asked Questions
Application Details
New to APHIS Funding?
Before you can apply, you’ll need to set up a Login.gov account, an ezFedGrants account, and be registered with the U.S. Government System for Award Management (SAM). Don't wait! It takes at least 10 business days for new SAM registrations to process.
Learn more about the basics of our funding process and how you can get ready to apply.
Use the templates and information below to develop your application package. All materials must be included, unless otherwise noted.
Application Package
Application packages must include a Work Plan and Financial Plan (see templates below). Packages must also include a completed SF-424, Application for Federal Assistance and SF-424-A, Budget Information for Non-Construction Programs; you’ll complete these forms within ezFedGrants.
Work Plan Template
Financial Plan Template
Eligible Entities
The following entities are eligible to apply for this funding opportunity:
- For-profit organizations, non-domestic (non-U.S.) entities (foreign organizations), and non-domestic (non-U.S.) components of U.S. organizations*
- Colleges and universities, including university research foundations
- State, national, allied, or regional producer organizations with direct or significant economic interest in poultry production
- State, national, allied, or regional veterinary organizations or specialty boards recognized by the American Veterinary Medical Association
- Federal agencies
- Nonprofits with 501(c)(3) IRS status, other than Institutions of Higher Education
- Nonprofits without 501(c)(3) IRS status, other than Institutions of Higher Education
- State departments of agriculture
- State emergency agencies
- Small businesses
* These entities require additional review and approval processes. For more information, contact us at sm.ap.hpai.challenge@usda.gov. Application Deadline
The application deadline is May 19, 2025, 11:59 PM EDT. Applications received after this deadline will not be considered for funding.
If you're a non-Federal applicant, you must submit all application materials via ezFedGrants. Locate this opportunity on ezFedGrants or on Grants.gov using the opportunity and catalog numbers found at the top of this page.
Apply Now: Non-Federal Applicants
If you're a Federal applicant, you must submit your application materials via email to sm.ap.hpai.challenge@usda.gov.
