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US Congressional Research Service - H5N1 Avian Influenza: The Human Health Response

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  • US Congressional Research Service - H5N1 Avian Influenza: The Human Health Response

    February 4, 2025


    Since early 2022, a U.S. H5N1 avian influenza (“bird flu”)

    outbreak in poultry and wild birds has led to outbreaks in

    dairy herds. Increasing cases of transmission from animals

    to humans occurred in 2024. H5N1 influenza is a subtype

    of influenza A virus that causes highly pathogenic avian

    influenza, a form of influenza that is highly contagious and

    deadly to birds. The virus has adapted to spread among

    certain mammal species such as cattle and cats. Currently,

    H5N1 influenza is not known to spread easily from human

    to human. To date, most human H5N1 influenza cases have

    been associated with animal exposures, with very few cases

    due to human-to-human transmission. Yet many

    uncertainties persist around if and when H5N1 influenza

    virus might adapt to spread more easily among humans,

    potentially resulting in a pandemic. In this case, most

    people would not have prior immunity to H5N1 influenza

    virus, which means the virus could spread quickly. The

    virus’s growing spread among animals creates more

    opportunities for a strain with human pandemic potential to

    emerge.

    continued: https://crsreports.congress.gov/product/pdf/IF/IF12895
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