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Source: http://www.cidrap.umn.edu/news-persp...an-jun-09-2017
News Scan for Jun 09, 2017
More Saudi MERS; Measles vaccine timing; Yemen cholera outbreak
Filed Under:
MERS-CoV; Measles; Cholera
Six new asymptomatic hospital MERS cases confirmed in Saudi Arabia
The Saudi Arabian Ministry of Health (MOH) reported six new cases of MERS-CoV today, all linked to one or more of the current hospital outbreaks in Riyadh.
The six patients are all women, all expatriates, and all healthcare workers who contracted MERS-CoV (Middle East respiratory syndrome coronavirus) at work. Their ages ranged from 26 to 48, and they are all in stable condition. None of the women were symptomatic.
Yesterday, the MOH reported five hospital-based cases in Riyadh. So far this month, there have been 27 cases in Riyadh with clear links to hospitals.
The new MERS cases raise the country's total since the outbreak began in 2012 to 1,630, including 671 deaths. Eleven patients are still receiving treatment.
Jun 9 MOH report
Review shows weaker measles immune response with earlier vaccination
Receiving measles vaccine earlier in infancy may be related to a poorer immune response compared with receiving it a bit later, findings that support US vaccine schedules, according to a meta-analysis published yesterday in Clinical Infectious Diseases.
Canadian investigators identified five randomized, controlled trials involving 5,542 children who were given the first dose of measles vaccine when they were 11 months to 22 months old. Four studies involved the tetravalent MMVR (measles-mumps-rubella-varicella) vaccine in 13 European countries in 2004 through 2008, while the other involved the trivalent MMV (measles-mumps-rubella) vaccine in the United States from 2010 to 2012.
The researchers found that, when they divided children by month of vaccination (11, 12, 13-14, and 15-22), the percentage of vaccine recipients testing seronegative for measles 6 weeks post-vaccination was 8.5%, 3.2%, 2.4%, and 1.5%, respectively.
Except for certain high-risk groups, the US Centers for Disease Control and Prevention recommends a first dose of MMR at 12 months through 15 months. A second dose should be given at 4 through 6 years of age, but it can be given earlier if at least 28 days have passed since the first dose.
The immune response to the vaccine, measured in geometric mean concentration (GMC), showed a similar pattern to the rates of seronegativity. The GMC varied from 1,835 milli-international units per milliliter (mIU/mL) in the youngest-vaccinated group to 3,562 mIU/mL in the oldest-vaccinated. The MMVR vaccine produced a stronger immune response across all groups. GMC for MMVR ranged from 2,051 to 4,199 mIU/ML, whereas GMC for MMR ranged from 1,188 to 2,751.
The authors noted that these effects persisted even after children received the second vaccine dose.
Jun 8 Clin Infect Dis study
Cholera cases in Yemen top 100,000
The World Health Organization (WHO) said today that cholera cases in Yemen have climbed past the 100,000 mark. As of Jun 7, there were 101,820 cases and 791 deaths reported.
According to the WHO, children younger than 15 account for 46% of the cases, and those 60 years old and older represent 33% of fatalities. Transmission is occurring in "cholera hot spots," conflict zones populated with displaced people.
Nearly half the hospitals in Yemen have closed in the last 2 years during conflict, and 4.5 million people do not have regular access to clean water and sanitation. The WHO said health and sanitation workers have not received their salaries in more than 8 months.
At least $66.7 million is needed over the next 6 months to establish oral hydration stations, provide chlorinated drinking water, and rebuild sanitation infrastructure, the agency said.
Jun 8 WHO press release
News Scan for Jun 09, 2017
More Saudi MERS; Measles vaccine timing; Yemen cholera outbreak
Filed Under:
MERS-CoV; Measles; Cholera
Six new asymptomatic hospital MERS cases confirmed in Saudi Arabia
The Saudi Arabian Ministry of Health (MOH) reported six new cases of MERS-CoV today, all linked to one or more of the current hospital outbreaks in Riyadh.
The six patients are all women, all expatriates, and all healthcare workers who contracted MERS-CoV (Middle East respiratory syndrome coronavirus) at work. Their ages ranged from 26 to 48, and they are all in stable condition. None of the women were symptomatic.
Yesterday, the MOH reported five hospital-based cases in Riyadh. So far this month, there have been 27 cases in Riyadh with clear links to hospitals.
The new MERS cases raise the country's total since the outbreak began in 2012 to 1,630, including 671 deaths. Eleven patients are still receiving treatment.
Jun 9 MOH report
Review shows weaker measles immune response with earlier vaccination
Receiving measles vaccine earlier in infancy may be related to a poorer immune response compared with receiving it a bit later, findings that support US vaccine schedules, according to a meta-analysis published yesterday in Clinical Infectious Diseases.
Canadian investigators identified five randomized, controlled trials involving 5,542 children who were given the first dose of measles vaccine when they were 11 months to 22 months old. Four studies involved the tetravalent MMVR (measles-mumps-rubella-varicella) vaccine in 13 European countries in 2004 through 2008, while the other involved the trivalent MMV (measles-mumps-rubella) vaccine in the United States from 2010 to 2012.
The researchers found that, when they divided children by month of vaccination (11, 12, 13-14, and 15-22), the percentage of vaccine recipients testing seronegative for measles 6 weeks post-vaccination was 8.5%, 3.2%, 2.4%, and 1.5%, respectively.
Except for certain high-risk groups, the US Centers for Disease Control and Prevention recommends a first dose of MMR at 12 months through 15 months. A second dose should be given at 4 through 6 years of age, but it can be given earlier if at least 28 days have passed since the first dose.
The immune response to the vaccine, measured in geometric mean concentration (GMC), showed a similar pattern to the rates of seronegativity. The GMC varied from 1,835 milli-international units per milliliter (mIU/mL) in the youngest-vaccinated group to 3,562 mIU/mL in the oldest-vaccinated. The MMVR vaccine produced a stronger immune response across all groups. GMC for MMVR ranged from 2,051 to 4,199 mIU/ML, whereas GMC for MMR ranged from 1,188 to 2,751.
The authors noted that these effects persisted even after children received the second vaccine dose.
Jun 8 Clin Infect Dis study
Cholera cases in Yemen top 100,000
The World Health Organization (WHO) said today that cholera cases in Yemen have climbed past the 100,000 mark. As of Jun 7, there were 101,820 cases and 791 deaths reported.
According to the WHO, children younger than 15 account for 46% of the cases, and those 60 years old and older represent 33% of fatalities. Transmission is occurring in "cholera hot spots," conflict zones populated with displaced people.
Nearly half the hospitals in Yemen have closed in the last 2 years during conflict, and 4.5 million people do not have regular access to clean water and sanitation. The WHO said health and sanitation workers have not received their salaries in more than 8 months.
At least $66.7 million is needed over the next 6 months to establish oral hydration stations, provide chlorinated drinking water, and rebuild sanitation infrastructure, the agency said.
Jun 8 WHO press release