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In a study conducted among nearly 500 influenza vaccine-naive mother-infant pairs in Malawi, researchers found that maternal HIV infection was associated with lower antibody responses to influenza A viruses in both mothers and their infants, suggesting that influenza vaccines “may have variable efficacy in sub-Saharan Africa” where there is a high burden of HIV, researchers said.
In the study, neither HIV nor malaria infection impaired transplacental transfer of influenza antibodies — one of the ways maternal vaccination protects infants — and malaria infection did not have a consistent impact on antibody levels in mothers or infants.
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In the study, neither HIV nor malaria infection impaired transplacental transfer of influenza antibodies — one of the ways maternal vaccination protects infants — and malaria infection did not have a consistent impact on antibody levels in mothers or infants.
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